The power of the Grail, now in the hands of the Laḫmu, has transformed the Persian Gulf into the Chaos Tide. Any living thing that touches this sea is instantly mutated into a Demonic Beast.

As the Chaos Tide advances toward Uruk, Fujimaru and company form a desperate plan to destroy Tiamat as a last-ditch effort to save the city.

Fujimaru and company finally succeed in defeating Beast II, though this victory was won with many sacrifices. The entire group is wounded and battle-weary, and as they take stock of the aftermath, they see that Uruk itself is on the verge of collapse. What will the end of their journey bring them?