A dangerous new drug is on the streets, and its addicts are causing trouble around town. Takashi enlists Makoto’s aid in dealing with the problem, and for Makoto, things soon become personal.

A woman abruptly commissions Makoto to get revenge for an attack that crippled her brother. But the "beast" who attacked him hardly seems savage, so Makoto decides to dig a little deeper on this case.

Now on the run from most of his former friends, Makoto has to use all the resources he has left to piece together who's causing so much trouble in Ikebukuro. Chances are, it's the same one who seems to have a personal grudge against him.