Professor Noel Fitzpatrick and his team return for an eleventh series. In the first episode, a tiny Jackahuahua puppy is in need of emergency spinal surgery after being attacked by a dog in the park, but it is not certain that he will be able to get back on his feet again after the operation. Elsewhere, a Bernese has a rare cyst in his elbow, requiring a challenging operation for removal, and an excitable Labrador requires elbow replacement surgery, which will result in a long and difficult road to recovery.

An overweight bulldog needs an operation on his knees, but first Noel and the team must fix his breathing defect - a a common problem with flat face breeds. Elsewhere, a pug requires risky emergency spinal surgery to remove a cyst, and a rescue dog with hip dysplasia may have to be let go while under anaesthetic.

Noel Fitzpatrick tries to save a tortoiseshell cat's leg by cutting out a tumour that has developed and replacing its knee with a unique bionic implant. Staffordshire bull terrier Rosie is admitted as an emergency after her back legs suddenly collapse in the park, and Noel performs essential spinal surgery to the diseased discs in Rosie's spine and advises a course of intense physiotherapy.

Professor Noel Fitzpatrick treats a Labrador puppy with an elbow disease, and believes a possible solution might involve fitted plates and stem cell injections. Elsewhere, a one-year-old cat is brought in suffering from a crushed pelvis and a broken tail after a road traffic accident, and a Russian Black Terrier with a cancerous growth is at risk of losing his leg.

This time, Take That's Mark Owen brings his 18-month-old Doberman, who needs treatment on a limp, into the surgery. Meanwhile, a four-year-old Coton-Tzu from Dublin with hip dysplasia may require a double hip replacement, and a Border Collie is brought in needing assistance with a problem with lameness.

Football pundit Lee Dixon brings his beloved rescue dog to see Professor Noel Fitzpatrick, looking for help treating a limp and getting his pet back to full fitness. Elsewhere, a Springer Spaniel all the way from Guernsey is brought in for spinal surgery, and a Caucasian Shepherd puppy called Bear requires two hip replacements.