Tom Parfitt doet alsof hij gewond is geraakt om aan zijn eentonige levensstijl te ontsnappen en naar een zorgcentrum te gaan. Bij zijn aankomst krijgt het personeel echter te maken met verschillende vreemde gebeurtenissen, waaronder een moord.

Tadashi Usobuki is a mysterious man with red eyes. He wears black suits with a wine-red shirt and possesses a special power which will drive people to their death through methods such as curses and brainwashing. However, it is impossible for his crimes to be proven in court, thus Usobuki cannot be taken to justice for the killings he did on behalf of his clients. Meanwhile, there is Tomoko Tada, a police detective and the only person who cannot be controlled by Usobuki.

The citizens of Happy Wheels, a town known for its insanely high death count, go on many misadventures as the Defensive Education Awareness Team and Health Society (D.E.A.T.H.S.) attempts to lower the town's death count.