Tadashi Usobuki is a mysterious man with red eyes. He wears black suits with a wine-red shirt and possesses a special power which will drive people to their death through methods such as curses and brainwashing. However, it is impossible for his crimes to be proven in court, thus Usobuki cannot be taken to justice for the killings he did on behalf of his clients. Meanwhile, there is Tomoko Tada, a police detective and the only person who cannot be controlled by Usobuki.

Tom Parfitt fakes an injury in order to escape from his monotonous lifestyle and head to a care center. However, upon his arrival, the staff experiences several strange instances, including a murder.

The citizens of Happy Wheels, a town known for its insanely high death count, go on many misadventures as the Defensive Education Awareness Team and Health Society (D.E.A.T.H.S.) attempts to lower the town's death count.