浪人刺客緋村劍心來到 1878 年的東京，在此意外結識了許多朋友，但仍舊擺脫不了令人聞風喪膽的過去。

來自冥河的外道眾出現在人間，對人類產生危害。打著“主公”名號的影武者志葉丈瑠將志葉家的家臣池波流之介、白石茉子、谷千明、花織琴葉集合在一起，為保護人類，以及阻止外道眾的破壞。這五名侍衛各自擁有自己專屬的折神，並且一路上找回了兜（獨角仙）、舵木（旗魚）、虎（猛虎）三個折神。之後丈琉的朋友梅盛源太也加入他們的行列。此外侍戰隊也遭遇來自假面騎士世界的拜訪，此外，故事後半段少年榊原弘將家傳的牛折神送給丈琉。

這隻正值青春期的兔子一心想成為真正的武士，他和新認識的戰士朋友組隊，合作保護城市不受妖怪、忍者、邪惡外星怪物侵害。

故事述說一位名叫百鬼丸的男孩，因為父親醍醐景光夢想稱霸亂世，於是在地獄堂與四十八隻魔神做出約定，將自己第一個出生的孩子的身體，分為四十八個部份，讓四十八隻魔神拿走。被親生父母遺棄在木桶中的百鬼丸飄流在河上時，遇見一位好心的醫生壽海。壽海以木頭和瓦片，替百鬼丸做了身體殘缺的部分和手腳，百鬼丸長大後為了拿回自己的身體，開始踏上討伐魔神的道路，途中遇上女扮男裝的小偷多羅羅，二人在亂世中展開與四十八隻妖怪戰鬥的冒險旅途。

Sakazaki Iwane is a ronin who spends idle days in Edo. Until a few months ago, he was a promising son and successor to a powerful family in Bungo. He has came back to Edo, where he lived for a while for swordplay training with his two best friends, after a tragedy in the three's home domain—both of the two friends died, one of them killed by Iwane by command of the domain lord's chief retainer. Iwane left his home for Edo, leaving behind his fiancée, a sister of the friend he killed. Eventually, Iwane detects the conspiracy behind the deaths of the two friends and struggles to reform his domain.

Wandering the lands of Japan - Ran is a master swordsman with a strong sense of honor combined with the courage and strength to right wrongs and battle injustice.​ But that doesn't stop her from having a good time!

Stuck with an unwanted traveling companion,​ Myao,​ the two will bring law and order to the countryside.​.. if they don't kill each other first.​ A comedic,​ action drama from start to finish - the way of the Samurai will never be the same!

Continuing the tradition of the Yojimbo movies, Mifune Toshiro stars as Toge Kujuro, a wandering ronin searching for his own fame and happiness. With a sense of justice, he travels the countryside, with his motley collection of outcasts - a pistol-carrying ronin, a two-bit con artist and woman seeking revenge, following close behind, unwittingly righting wrongs and protecting the common man.