Efter at være blevet diagnosticeret med kræft og givet blot to år tilbage at leve i forsøger kemilæreren Walter at sikre sin families fremtidige økonomiske situation ved at slå sig sammen med en tidligere studerende, Jesse, for at producere og sælge det ulovlige stof amfetamin. Mens Walter langsomt bygger sit imperium op, begynder hans kone Skyler at undre sig over hans uregelmæssige adfærd, og politiet sætter jagten ind på kvarterets nye bagmand.

Matador chronicles the unlikely rise of Tony "Matador" Bravo, a popular soccer star who comes to be known as much for his playboy antics off the field as his dynamic moves on it. But what his fans and family don't realize is that it's all a cover—in truth, he is a skilled covert operative executing missions for a little-known branch of the CIA. “Matador” has the kind of fame and notoriety that affords him access to powerful circles of corruption and villainy. But, in balancing the dueling roles in which he's been cast, he will be forced to confront the question of his true identity… and it is this mission which will prove to be his most dangerous.

The story of how one company triggered the worst drug epidemic in American history. Look into the epicenter of America's struggle with opioid addiction, from a distressed Virginia mining community, to the hallways of the DEA, and to the opulence of "one percenter" Big Pharma Manhattan.

Faktabaseret historie om undercover DEA agent Enrique "Kiki" Camarena der, mens udstationeret i Guadalajara, afdækket en massiv marihuana operation i det nordlige Mexico, der førte til hans død og en bemærkelsesværdig undersøgelse af korruption i den mexicanske regering.