Po ponovni združitvi z Gwen Stacy prijazni človek-pajek Miles Morales iz Brooklyna prepotuje multivesolje, kjer naleti na ekipo sorodnih pajčjih ljudi, zadolženih za zaščito njegovega obstoja. Toda ko se med junaki vname spor o tem, kako naj se spopadejo z novo grožnjo, se Miles znajde v boju z drugimi pajki in mora na novo opredeliti pomen junaštva, da bo lahko rešil ljudi, ki so mu najbolj pri srcu.
Najstnik Peter Parker v šoli nikakor ne najde pravih prijateljev, razumevanje najde le pri dolgoletni prijateljici Gwen, ki ji brez uspeha skuša izpovedati svoja ljubezenska čustva. Življenje se mu postavi na glavo, ko odkrije kovček dolgo pogrešanega očeta. Ker želi raziskati očetovo izginotje, ga sledi vodijo do očetovega nekdanjega sodelavca, dr. Connorsa, toda soočenje z njegovimi nenavadnimi poskusi Petra spremeni v superjunaka.
A large spider from the jungles of South America is accidentally transported in a crate with a dead body to America where it mates with a local spider. Soon after, the residents of a small California town disappear as the result of spider bites from the deadly spider offspring. It's up to a couple of doctors with the help of an insect exterminator to annihilate these eight legged freaks.
Po skrivnostnem poginu živine farmerja Walterja Colbyja pošlje veterinar dr. Rack Hansen vzorce krvi na preiskavo na univerzo. Nekaj dni pozneje ga obišče znanstvenica dr. Diane Ashley in pove, da je živali ubila velika količina pajkovega strupa. S sprva nejevernim Rackom se opravita na Walterjevo kmetijo in na njegovem polju odkrijeta velikansko pajkovo gnezdo. Kmalu ugotovijo, da je vse mesto obkoljeno z neskončnim številom ubijalskih pajkov in prebivalci nimajo nobenega izhoda iz te pasti.
When a team of backpackers sets out to explore the Indian jungles, one of them is bitten by a poisonous spider and killed.
An airplane carring coffee beans from South America has some unpleasant stowaways: a hoard of tarantulas which overcome the pilots as the airplane is flying over an orange-producing town in California. The airplane crashes, and the unlucky inhabitants of the town release the poisonous spiders into their midst. Once the town's officials discover that the tarantulas are responsible for several deaths, the tarantulas have already descended upon the town's only orange-processing factory. The town's citizens risk their lives to remove the tarantulas from the factory while the poisonous pests are rendered motionless by the transmitted sound of buzzing bees
A doctor is driven into an investigation of sinister goings-on at a horse race track by his mystery writer ex-wife.
The Iron Cross Army are sabotaging oil-tankers with the help of their monster, the Sea-Devil, a semi-mechanical anthropomorphic swordfish with an ability to shoot torpedoes from its mouth. Spiderman employs the help of the interpol agent Juzo Mamiya to help him stop the Iron Cross Army.