在不久的将来，随着地球上的冲突不断地爆发，国际空间站上的紧张局势也在加剧。 令人震惊的是，美国和俄罗斯宇航员都收到了来自地面的命令：采取任何必要手段控制空间站。

　　火箭工程师卡格雷夫斯博士在测试期间炸毁了一枚火箭，并因此失去了政府资助。 他们与他的朋友塞耶将军、吉姆·巴恩斯将军一起，从某位美国企业家那里筹集资金，在沙漠中使用原子发动机制造火箭以求到达月球。 但是，公众明显反对该项目，因为该项目极有可能会发生核泄漏，使得他们决定不进行测试的情况下就直接进行飞船的发射。

Lester and Orville accidentally launch a rocket which is supposed to fly to Mars. Instead it goes to New Orleans for Mardi Gras. They are then forced by bank robber Mugsy and his pal Harry to fly to Venus where they find a civilization made up entirely of women, men having been banished.

The band OK Go gives viewers a look at the behind-the-scenes work -- and 21 flights -- that went into filming their famous zero-gravity music video.