Dr. Megan Hunt was in a class of her own, a brilliant neurosurgeon at the top of her game. But her world is turned upside down when a devastating car accident puts an end to her time in the operating room. Megan resumes her career as a medical examiner, determined to solve the puzzle of who or what killed the victims.

Betjenten Nikki Batistas og eksmanden Jason Grants søgen efter at afdække sandheden om deres forsvundne søn bringer dem på hjerteskærende eftersøgninger i håbet om at hjælpe andre i samme situation.

Omameda Towako recently become the president of the construction company "Shirokuma Housing". She has experienced three divorces and is currently living with her 15-year-old daughter, Uta. Although Towako has been divorced thrice, she remains bright and lives her life strongly. However, her life is constantly disrupted by her three troublemaker ex-husbands.

After eighteen years of marital life, Fran is shocked when her husband reveals that he is gay. Living under the same roof, the two of them date various men.

The series is about three men aged between 35 and 45 who are in the middle of a divorce. They decide to temporarily live together. They share joys and sorrows, and a deeply rooted friendship grows. The story revolves around everything that a divorce entails: the strong emotions, the quarrels, the mourning, the doubts, the children, finances, rediscovering yourself, starting again, dealing with your ex and dating on your fortieth. But the series is also about a typical male friendship. Men who need but a few words to understand each other, who give each other space to be sad and who back each other up when they are vulnerable. But also men who are not afraid to tell each other the brutal truth.

Den nyligt fraskilte 41-årige Toby Fleishman kaster sig ud i app-baseret dating med en succes, han aldrig oplevede i sin ungdom. Så forsvinder hans ekskone og efterlader ham med deres to små børn og ingen antydning af, hvor hun er, eller om hun planlægger at vende tilbage.

Alistair og Joanna rejser til Australien med deres lille barn for at ansøge om myndigheden over Alistairs datter. Da de ankommer til Australien rammer en tragedie, som ændrer deres liv og ægteskab for evigt - deres lille dreng forsvinder under en køretur. Dernæst følger en rejse ind i en ung kvindes smuldrende sind, der blotlægger myter og sandheder om moderskabet.