Seymour Krelborn is a nerdy orphan working at Mushnik's, a flower shop in urban Skid Row. He harbors a crush on fellow co-worker Audrey Fulquard, and is berated by Mr. Mushnik daily. One day Seymour finds a very mysterious unidentified plant which he calls Audrey II. The plant seems to have a craving for blood and soon begins to sing for his supper.

Нескопосаният помощник на Дявола не му е довеждал нито една душа за последните 1400 години, затова му дават един последен шанс да вземе душата на комарджия от Лас Вегас.