Engang var den blomstrende hjemsted for den farmaceutiske gigant Umbrella Corporation, Raccoon City er nu en døende by i Midt vesten. Virksomhedens udvandring efterlod byen en ødemark ... med stor ondskab under overfladen. Når den ondskab bliver sluppet løs, er bybefolkningen for evigt...forandret...og en lille gruppe overlevende må arbejde sammen for at afsløre sandheden bag Umbrella og klare sig igennem natten.

Den garvede Cleveland-strisser "Big Bob" Carter og hans kone Ethel fejrer deres sølvbryllup med en campingtur til Californien sammen med deres nærmeste: datteren Lynn og hendes mand Doug- og deres spædbarn Catherine - samt teenagerne Brenda og Bobby. Alt går efter bogen, indtil Big Bob får den id‚ at skyde genvej gennem ørkenen. Da bilen bryder sammen, går det langsomt op for dem, at den er helt gal. De er ikke så alene, som de først troede. For gemt væk i ørkenen bor en gruppe overlevende fra de amerikanske atomprøvesprængninger i 1950'erne - hæslige, glubske, blodtørstige misfostre, som kaster sig over den lille familie

En flok venner er på vej til en college football-kamp og kører forkert. De ender hos to morderiske brødre i en lille forladt spøgelsesby. Der opdager de til deres store skræk, at brødrene har udvidet byens største attraktion – vokskabinettet – til at omfatte hele byen! Andre vildfarne uheldige forbipasserende er endt som voksdukker, og nu må vennerne kæmpe for livet for ikke selv at ende som en del af den permanente udstilling!

Sharon er psykisk syg, og lægerne anbefaler indlæggelse på livstid. Det vil hendes mor Rose ikke høre tale om, så hun søger tilflugt i Silent Hil, en uhyggelig spøgelsesby, der altid er indhyllet i tåge og fuld af skumle væsner. Sharon bliver kidnappet og Rose beslutter at sætte hårdt mod hårdt i forsøget på at redde sin datter og komme en lurende ondskab til livs.

Mars, 2025. Politiassistent Ballard skal transportere den højkriminelle Desolation Williams til hovedstaden på Mars, hvor 640.000 mennesker bor og arbejder. Planeten har store naturlige rigdomme, men også ruiner fra en civilisation af krigeriske marsmænd, hvis ånder er i gang med at ødelægge alle planetens nuværende beboere. Ballard erfarer snart, at de eneste overlevende er Williams og andre kriminelle fra et afsidesliggende fængsel. Kun ved at samarbejde kan de overleve.

Den unge racerkører Jim Douglas har aldrig haft specielt stort held med sine biler... før han en skønne dag møder en lille hvid “asfaltboble”, som helt kommer til at forandre hans liv. Den lille Herbie kører helt sine egne veje, og efter princippet: Den lille og vågne narrer den store og dovne! Forrygende sjov... Herbie fræser lige ind i alles hjerter!

Da den populære horror-forfatter Sutter Cane forsvinder, bliver forsikringsagenten John Trent sendt af sted for at se nærmere på omstændighederne. Hans undersøgelser bringer ham til den lille by Hobbs End, hvor Canes rædselsvisioner tilsyneladende udspiller sig i virkeligheden.

Jake Wade breaks Clint Hollister out of jail to pay off an old debt, though it's clear there is some pretty deep hostility between them. They part, and Jake returns to his small-town marshal's job and his fiancée only to find he has been tracked there by Hollister. It seems they were once in a gang together and Jake knows where the proceeds of a bank hold-up are hidden. Hollister and his sidekicks make off into the hills, taking along the trussed-up marshal and his kidnapped bride-to-be to force the lawman to show them where the loot is.

A man wanders into a seemingly deserted town with his young son in search of work. But after a bit of bad luck, he joins the town's population of lost souls.

A group of people on a rafting excursion happen upon a deserted town and decide to set up camp. Out of the blue, a murder occurs.

Sabrina's perfectly planned high school reunion goes south when a monster keeps killing all the guests.

Seraphim Cloud and his life size doppelgänger enter the netherworld of Calico Ghost Town deep within the Mojave Desert.

A 40-day, 40-night road trip to the Trinity Site—where the first atomic bomb was detonated in the summer of 1945—covering many other atomic destinations and driving deep into the natural and social history of the American southwest.

A starving cat wandering in the wilderness sees a sign that says "Ma's Place / Home Cooking / 3 Miles". The cat speeds into town, without noticing the sign that says "Ghost Town / Population 100 Ghosts". One of these ghosts is a mouse eager to get revenge on cats for having tormented him in life.

In a future where cities have crumbled and been reclaimed by nature we join a lone man exploring the ruins of the company Haven Nanosystems. Recovering a locked container he seems to have found what he was looking for, which is information relating to the quarantined Facility B. Unfortunately just as located by a robotic drone and the race to escape is on.

Tom Andrews, his wife Kathy, their two children & Tom's Father Henry are all driving to a town called Silversprings on Christmas Eve to visit relatives. On the way, they decide to stop at a ghost town called Sutterville which by a strange coincidence Tom has had nightmares about every year around Christmas for his whole life. Tom's father is wary & begs them not to go; however Tom's car develops a mind of it's own & takes them there only to break down so that they can't leave. Meanwhile a man arrested for vagrancy by local police is identified as Clarence McCoughlin who supposedly died in Sutterville 40 years ago, not to mention he seems to have some sort of demonic power. As the Andrews family explore the town a feeling of unease starts to takeover, Clarence escapes jail & heads back to Sutterville for a sinister family reunion...

On their way to Cabo San Lucas, the cast and crew of a low-budget film get lost and come upon "La Sangre De Dios", a ghost town with a spine-tingling legend about an insane Mexican wrestler. One by one, the cast and crew are snatched, beaten and dragged to a bloody death. The few left alive must figure out how to beat the wrestler at his own deadly game, or die trying.

When his mother Dolores dies, Juan Preciado, son of Pedro Páramo, goes to Comala to claim his inheritance; but when he arrives he finds an abandoned and sinister place, inhabited by mysterious voices and whispers…

Real Haunts: Ghost Towns reveals the secrets of America's most fascinating ghost towns with "The Beard of Knowledge", the residents and a family of ghost hunters.

A rich stockbroker buys a Nevada ghost town as a community for people who need a second chance in life.