十八歲的羅娜 (莎拉波利飾演) 在超級市場當收銀員。快要被房東趕出去的她，極需要本短期內湊出一筆錢繳房租。正巧，超市裡另一名癮君子收銀員-賽門，因為出外旅行，於是請羅娜代班。在毫無其他辦法可想之下，羅娜決定挺而走險假冒她的毒販同事-賽門，好好撈一票。 亞當史考特霍夫飾演) 與賽克 (傑莫爾飾演) 是兩個因吸毒而被警察逮捕的電視小演員。為了將功贖罪，也們只好假扮成癮君子，配合警察追捕毒梟，剛好碰上羅娜的第一次交易。 賽門(戴斯蒙亞斯吉飾演) 與二名好友一同開車前往拉斯維加斯玩樂。在短短幾小時內，這四個人犯下了，縱火、偷竊、殺人未遂等多項名堂，而再他們及於逃離賭城時，更大的災難正在等著他們。
Jane, a struggling but perpetually stoned actress, has a busy day ahead. She has several important tasks on her list, including buying more marijuana. Even though she already has a good start on the day's planned drug use, she eats her roommate's pot-laced cupcakes and embarks on a series of misadventures all over Los Angeles.
Brian comes under the addictive spell of a parasite with the ability to induce euphoric hallucinations in its hosts.
Cocaine has always gotten a bad rap, and for a reason. It is a drug used by the rich and the poor legally and illegally, Mexican cartels fought over it with Colombia once associated with the brutal cocaine wars, and a source of tension between the American and Mexican borders on the people who are illicitly bringing in cocaine from one side of the border to another and will do anything to do it. So it can be surprising at times to the viewer throughout the course of the documentary special, that it was never always like this.
An educational film from 1967 designed to scare teenagers away from illegal drugs
A man wants to fly in the air like his friend
Documentary about human experiments conducted at the Veterans Hospital in Palo Alto, California in the 60's, scientific studies about the effects of pure THC.
Heroin anti-drug educational film
A whole bunch of crazy things happen one night at a house party, much of it centering around a car where people go to smoke weed.
First timer Aaron goes to buy from a sketchy dealer, when he's invited inside a weird friendship starts to blossom. Until everything begins to spiral out of control.
A Teenager waiting for his dealer to arrive but is taking a while.