Un antropólogo de Harvard es enviado a Haití para investigar una extraña sustancia relacionada con la magia negra y el vudú, que podría servir para salvar vidas humanas. Mientras él busca la milagrosa droga, ciertos científicos escépticos se niegan a aceptar la existencia de zombies y ritos sangrientos.

Four friends break into an abandoned insane asylum in search of a death certificate which will grant one of them a large inheritance. However, finding it soon becomes the least of their worries in a place haunted by dark memories.

Madhavan Mahadevan, who comes into the city from a village to see off his sister-in-law and her daughter after the death of his elder brother, an upright Customs Officer (KB Ganesh Kumar). While running around to claim the insurance money, he comes to know that his brother was actually murdered by the underworld don Irumbanakkal John (Joy Mathew).