Disregard for alchemy’s laws ripped half of Edward Elric’s limbs from his body and left his brother Alphonse’s soul clinging to a suit of armor. To restore what was lost, the brothers seek the Philosopher’s Stone. Enemies and allies – the corrupt military, the Homunculi, and foreign alchemists – will alter the Elric brothers course, but their purpose will remain unchanged and their bond unbreakable.

Two young brothers are raised as alchemists, but when they are severely injured trying to perform a forbidden act, they begin searching for the one thing that can save them; the fabled philosopher's stone.

Ryza is an ordinary girl. Tired of boring village life, she escapes the village to gather with her good friends in a secret location to talk of their dreams and plan thrilling adventures. One day, the determined Ryza and company decide to head for the forbidden "island across the shore" as their first exploration trip. Together with the alchemist and other friends they meet there, they have a "summer adventure" that they will never forget.

In New York City, a teenage tracker makes his living selling hard-to-find mystical items to sorcerers — but dealing in magic can be risky business.