偵探 Patrick Jane 是加州調查局（CBI）專案調查組的獨立顧問，他利用自己的超感特長連續破獲了多起公眾關注度高的疑難懸案，驚人的破案效率和成功記錄讓很多人連呼神人。而生活中是個缺乏紀律感、不願意按規矩辦事的傢伙。

提姆羅斯飾演卡爾萊特曼博士，世界上數一數二的測謊專家，研究面部表情和無意識肢體語言，不僅能發現誰在說謊，還能找到原因。基於保羅埃克曼博士真實科學研究改編，在本劇中由萊特曼和他的測謊專家團隊，幫助執法機構與政府部門揭露謊言背後的真相。

Clinical psychologist Dr Tony Hill's uncanny ability to see into the minds of murderers means he finds it difficult to distance himself from disturbing cases.

FBI agent Angela Clinton has the exceptional gift of knowing when someone is lying. She discovered this skill at age 14, when she learned her "average" American parents were actually spies. Attempting to right her parents' wrong, Angela is now working with the same agency that brought her parents down.

Crime drama based on the UK TV series about Gerry "Fitz" Fitzgerald, a brilliant but troubled criminal psychologist working alongside the Los Angeles police department.