辛格尔顿•凯西已经40岁了，她没有结婚，没有固定的男朋友，但是她喜欢孩子，她希望成为一个母亲。所以，凯西决定进行人工受精。虽然这个决定遭到了她最好的朋友沃利的反对，但是凯西依然决定要去找一个捐精者，她执意要怀孕。在现代医学的帮助下，凯西很快找到了合适的捐精人－－英俊潇洒的罗纳德。在找到精子的来源之后，凯西决定为自己开一个“受孕派对”。

虽然沃利对凯西一直有所牵挂，虽然他一直爱慕着凯西，但是这个有些神经质的男人已经错过了向凯西表白的最佳时刻，而凯西现在也仅仅只是把他当做自己的朋友，而不是情人，更不是结婚对象。以想象，在“受孕派对”上见到帅气的罗纳德之后，沃利有多么的失落。多喝了几杯之后，沃利进了厕所，阴差阳错之中，他失手倒掉了罗纳德捐献的精子。惊恐、无奈之下，他只好用自己的精子取代了罗纳德的精子。

7年之后，凯西带着自己的那个有点神经质、又有点早熟的儿子塞巴斯蒂安回到了纽约居住。她和沃利见面，让自己的孩子叫他沃利叔叔。沃利和萨巴斯蒂安不但外貌上很相似，就连小动作、小脾气都非常类似。看起来，沃利这回总有机会向凯西表白了－－她甚至都生了自己的孩子。可是，麻烦就在这里：罗纳德也出现在了凯西的生活中。

沃利最终能把凯西揽入怀中么？他能让塞巴斯蒂安叫自己爸爸么……

被俘虏的人，面对即将到来的处决，五十个陌生人被迫选择一个值得生活的人。

Alyssa wakes up in a home that's not hers and discovers a dead body. With no memory of how she got there, and no idea of who he is, Alyssa tries to piece together what exactly happened the night before.

John is a brilliant linguistic scientist with a loving wife and daughter but with a massive gap in his life. Eight years ago, he turned up out of nowhere, with no memories except a recurring dream. He is sent tumbling down the proverbial rabbit hole after meeting a man that shares a similar condition and learning that there are more like him, all amnesiacs with extraordinary abilities. He convinces his brother-in-law, private investigator Carl, to help him uncover his true identity before his past can rise up to destroy him and his family.

Jane Ravenson finds herself in the middle of a grocery store with $10,000 in her coat pockets and no memory of her life or who she is. Her husband eventually finds her and she starts to believe that her family life is fine until she feels a deep, nightmarish paranoia that something is horribly and terribly wrong.