辛格尔顿•凯西已经40岁了,她没有结婚,没有固定的男朋友,但是她喜欢孩子,她希望成为一个母亲。所以,凯西决定进行人工受精。虽然这个决定遭到了她最好的朋友沃利的反对,但是凯西依然决定要去找一个捐精者,她执意要怀孕。在现代医学的帮助下,凯西很快找到了合适的捐精人--英俊潇洒的罗纳德。在找到精子的来源之后,凯西决定为自己开一个“受孕派对”。
虽然沃利对凯西一直有所牵挂,虽然他一直爱慕着凯西,但是这个有些神经质的男人已经错过了向凯西表白的最佳时刻,而凯西现在也仅仅只是把他当做自己的朋友,而不是情人,更不是结婚对象。以想象,在“受孕派对”上见到帅气的罗纳德之后,沃利有多么的失落。多喝了几杯之后,沃利进了厕所,阴差阳错之中,他失手倒掉了罗纳德捐献的精子。惊恐、无奈之下,他只好用自己的精子取代了罗纳德的精子。
7年之后,凯西带着自己的那个有点神经质、又有点早熟的儿子塞巴斯蒂安回到了纽约居住。她和沃利见面,让自己的孩子叫他沃利叔叔。沃利和萨巴斯蒂安不但外貌上很相似,就连小动作、小脾气都非常类似。看起来,沃利这回总有机会向凯西表白了--她甚至都生了自己的孩子。可是,麻烦就在这里:罗纳德也出现在了凯西的生活中。
沃利最终能把凯西揽入怀中么?他能让塞巴斯蒂安叫自己爸爸么……
被俘虏的人,面对即将到来的处决,五十个陌生人被迫选择一个值得生活的人。
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