Two years after choosing not to kill the man who killed his son, former police sergeant Leo Barnes has become head of security for Senator Charlene Roan, the front runner in the next Presidential election due to her vow to eliminate the Purge. On the night of what should be the final Purge, a betrayal from within the government forces Barnes and Roan out onto the street where they must fight to survive the night.

Given the country's overcrowded prisons, the U.S. government begins to allow 12-hour periods of time in which all illegal activity is legal. During one of these free-for-alls, a family must protect themselves from a home invasion.