La serie está ambientada en un futuro próximo. Yuma Tsukumo es el número uno chico malo en su escuela. Algo inesperado sucede como Ryoga Kamishiro lo reta a un duelo. Cuando la misteriosa entidad astral aparece ante ellos una nueva leyenda comienza.
Aichi Sendō is a timid third-year middle school student who has always lived his life looking backwards rather than forward. However, he has a card called "Blaster Blade" that was given to him when he was little, which is the sole thing that sustains him. Then Kai Toshiki, a cool-hearted high schooler, introduces Aichi to a card game called "Vanguard". When participants battle they picture they are on a planet called "Klay", and since Vanguard features a never before seen game system it has become popular around the world. Aichi immediately likes Vanguard, so he begins to play it with his friends Misaki Togura and Kamui Katsuragi, and others like his new rival Kai (who is one of the best Vanguard players). Aichi plays every day and he strives with all his soul and heart to play better, so when he battles Kai, Kai will recognize Aichi's worth.
Yu-yu Kondo, un estudiante de tercer año de secundaria, vive en la ciudad de Kanazawa, en el país de Kaga. Al no poder rechazar las solicitudes, Yu-yu a menudo se ve envuelto en los pasatiempos de su hermana. Cuando Yu-yu ya no pudo soportarlo y huyó de casa, fue salvado por Megumi Okura. Megumi lo invita al parque de atracciones nocturno "Wonder Hill", donde se reúnen sus amigos. El parque de atracciones es donde se reúnen muchos jóvenes del grupo centrado en Vanguard "Team Blackout". Y así es como Yu-yu conoce Vanguard y se siente atraído por el atractivo de Vanguard y el mundo y los amigos que nunca había visto antes.
Hajime Hinobori is a grade 7 student who loves Battle Spirits. His parents leave him to research Battlefield Systems for the International Battle Spirits Association. Hajime is left under the care of their dear friend Dr. Denjiro. Then, Hajime finds a completed a Battlefield System demo machine. He will now fight as a Test Battler and is incredibly excited by the Spirits materialized in the Battlefield!
Bashin is a grade 6 student who loves trading card games. The globally popular card game Battle Spirits is all the rage. Through some strange circumstances, Bashin acquires a Pyroxene which gives Bashin the ability to become a Card Battler. He can summon the monster Spirits depicted on the cards so they can fight each other. Bashin learns that the legendary X Rare Card actually exists, and he engages in fierce card battles with other rivals to get the X Rare Card.
Dan is teaching young Battle Spirits fans about the cards, but he is suffering from a thirst he cannot quench. “I want fierce battles! I want to fight someone even stronger!!” And then Mai appears. She asks him to come with him to an era in which he can Battle. The new stage for Dan’s fights is the future. The Earth is being encroached on by Otherworld Mazoku monsters. He reunites with the administrator Kazan who asks him to rescue humanity from the brink of disaster.
In a new era of Battle Spirits, cards are treasures scattered throughout space. Adventurers called Card Questers battle against each other seeking out more and more powerful cards. The extremely tenacious Card Quester Rei and his beloved little dragon Mugen take off into the vast panoramas of space, blasting through the stratosphere of wild stars in the Star Number One. Rei masters various ultimate attributes, and transforms according to attribute colors!
Shunta, a boy who loves Battle Spirits, is led by a card and called to the “Spirits World” in another dimension. Eto, the priestess who summoned Shunta, warns of the Spirits World’s demise due to the evil God-King’s resurrection. In order to stop it, she says they must bring back together the twelve God-Kings for their powers. Joined by Yoku Albatrosa, a boy summoned from another dimension, Shunta is led by Eto on a journey to find the twelve God-Kings who are scattered throughout the world.
Han pasado dos años desde la insurrección de Mauve.
Gallet Revolt, quien aterrizó en Grand Rolo luego de su batalla con Vizarga, ha experimentado grandes cambios en sus ideales. Mientras estaba en el "mundo blanco", Gallet conoce a cierto joven.
Mientras tanto, Varte Parx, quien surgió como el líder de Mauve, utiliza su fortaleza aérea para ejercer presión sobre el Gobierno Unificado. El enfrentamiento entre el Gobierno Unificado y Mauve continúa intensificándose.
¿Podrá Gallet cambiar el futuro establecido en los Registros del Otro Mundo? La rueda del destino continúa girando, y el mundo finalmente entra en una época de cambio.
It is the year 2030, and the stage is the capital of Japan, Chou-Tokyo. Through "Buddyfight", humans have started cultural interactions with residents from other worlds called "Affinity Dimensions". Buddyfight is a game with selected humans as the "Buddyfighter", and residents from the other world as the partner (known as "Buddy Monster"). These battles have high significance and sometimes it is even used to decide the fate of a nation, and naturally there are those who seek to use the Buddy Monsters for evil purposes.
The year is 2661 CE. Ten years ago, Bashin Dan became the trigger that stopped the Earth from resetting itself. On the anniversary of this sacrifice, Barone and Clackey hold a conference, celebrating the union of Mazoku and humanity, and also Dan's feats.
However, beneath that peace, an organization named Cardinal Sign advocates for the subjugation of Mazoku and human supremacy. They resort to terrorist attacks, violence, and have somehow obtained the 12 Zodiac X-Rares which ought to have vanished together with Dan.
Amidst all this chaos, the bearers of the core's light feel a weird sensation, one that they've felt before. What could be the meaning of it, and what is the meaning behind the card that appeared within their decks, named "The Clash King's Miracle"?
The series follows the adventure of Bearers of Light's Core that will shape the destiny of the world.