A virus has decimated humankind. Those who survived emerged blind. Centuries later when twins are born with the mythic ability to see, their father must protect his tribe against a threatened queen.

Ages ago, the goddess Athena was served by fighters called Saints who channeled the power of the Cosmos within them. Now a youth named Seiya has trained to become a Saint himself by earning the mystical Cloth of Pegasus. He is joined by other Saints with Cloths of their own to fight for Athena.

The Bronze Saints enter the deepest realm of the Underworld, Elysion, where they face off against Hades's two most powerful servants, The Twin Gods, Hypnos and Thanatos, before they can reach Hades for the final battle.