Once again tampering with mother nature to disastrous results, Dr. Herbert West continues his research while serving time in a maximum security prison for his previous exploits. West's limited prison-cell experiments are suddenly interrupted by the arrival of a new prison doctor and the brother of the girl who suffered from West's experiments 13 years earlier.
When Dr. Frankenstein is killed by a monster he created, his daughter and his lab assistant continue his experiments.
Dr. Frankenstein is left for dead in the woods. His daughter, Dr. Vera Frankenstein, hunts for his attacker: Dr. Cagliostro, a mad scientist who’s created a race of human-animal hybrids.
Features interviews with the cast and crew of Re-Animator (1985), except for the late David Gale.
The six-decade transformation of a block of houses, shown by means of artfully featured archival shots, highlights the beauty and sadness of human-made decay. In the blink of an eye 66 years pass by and a savings bank replaces a church.