Το λιοντάρι Άλεξ, η ζέβρα Μάρτι, η καμηλοπάρδαλη Μέλμαν, ο ιπποπόταμος Γκλόρια και τρεις... πιγκουίνοι, ενώ έχουν ζήσει όλοι τους τη ζωή σε ένα ζωολογικό κήπο, κατά λάθος αποβιβάζονται στα παράλια της Μαδαγασκάρης. Εκεί, θα διαπιστώσουν ότι η ζωή στην άγρια φύση δεν είναι καθόλου εύκολη, ακόμα και για τα πιο... άγρια ζώα!

Ενας κατάδικος του έτους 2035 στέλνεται στο παρόν για να βρει τα αίτια της διάδοσης ενός θανατηφόρου ιού, που αφάνισε δισεκατομμύρια ανθρώπους.

A sinister corporation loses control of a house cat infected with a genetically-engineered virus. The death-toll rises during the mutant feline's rampage, and eventually, it finds its way on board a ship of a criminal king-pin.

A zoo veterinarian gets caught up in a grisly adventure as she finds herself leading the city-wide hunt for a monstrous lion terrorizing the Dutch capital of Amsterdam.

A tiger escapes from a circus truck as it passes by a small town, and hides itself in the surrounding woods. This throws the town into a panic and everyone wants the animal killed immediately, except for the daughter of the sheriff. She wants to capture the tiger and put it in a zoo, thereby saving the tiger's life. Her determination starts a nationwide campaign among children to raise the money to buy the tiger from the circus, but first, she, her father and an Indian tiger trainer must find the tiger before the National Guard do, who have orders to kill it on sight.

A young boy lets the animals out of their cages at the Zoo, to set them free, but the animals start taking over the town.

A wildcat escapes from the zoo, disguises herself as a skunk to fool her pursuers, but that only attracts lovestruck Pepe le Pew.

Panic grips a small community after a tanker truck crashes through a fence at a wild animal park, freeing dozens of dangerous beasts.

In this Pete Smith Specialty short, two lion cubs escape from the zoo and go on an adventure.

A witness to his mother’s death at the hand of a man, the coyote, Chico, has learned to hate and fear him. Taken into captivity and exhibited in a small desert roadside zoo, he learns much but never loses his bitterness toward his enemy: man. Chico makes his escape and bounds off for a life of adventure in the desert where he mates with Tula. He sees an eagle grab one of his pups and worries when his mate raids a chicken coop. Realizing the dangers of man, Chico decides to take his family deeper into the desert to help his family try to win the battle for survival.

In a small village in north of Sweden lives a calf that dislikes enclosures. The desperate farmer builds fence after fence, but the calf still manages to get out. When a film team arrives to make a film about the events, everything changes.