At the Death Weapon Meister Academy, three teams must collect the souls of 99 evil humans and one witch.
The human world is attacked by the space outlaw group the Dethgaliens who have chosen the Earth to be the site of their 100th Blood Game. One human and 4 anthropomorphic Zyumans awaken their instincts to become the Zyuohgers and fight to protect all living things.
Hakuoro has lost his memory after succumbing to serious injuries. But thanks to an elderly woman and her granddaughter Eruruu, he is nursed back to health. His face is covered by a strange irremovable mask and he occasionally sees beastly visions. Eruruu now cares for him as he becomes accustomed to the village and its inhabitants, who all bear strange ears (the women also have tails). Though these people venerate the forces of nature, desecration of an altar forces them to take drastic measures to preserve their lives from the wrath of Mutikapa-sama, guardian of the forest.
Nice guy Kio’s normal life gets turned upside down when he meets a friendly, sexy cat-alien named Eris. She’s on a peaceful mission—and she’s ready to play. Things get even friskier when her fellow felines set up base in Kio’s house. It’s not all fun and games, though. Danger is afoot, thanks to several secret agencies and enemy dog-aliens on Eris’s tail.
Kashou Minaduki is an aspiring chef who moves away from home to open his own confection shop. While he is unpacking in his new shop, he discovers that two of his family's Nekos, Chocola and Vanilla, came along with him by hiding in cardboard boxes. After the two Nekos convince Kashou to let them stay and live with him, the three of them work together to run his shop, La Soleil. During the story, Kashou receives a couple of visits from his younger sister Shigure and the other four Nekos owned by their family.
In the midst of a war between the families of Demitri Maximoff and Morrigan Aensland for control of the Demon World, alien invader Pyron arrives on Earth and plans to take it over by taking out those who stand a chance of stopping him, namely the Darkstalkers. Meanwhile, dhampir Donovan Baine seeks to rid himself of the cursed blood which runs through his veins.