Eve Polastri, eine MI5-Sicherheitsoffizierin, wird zur Leiterin einer kleinen, geheimen Undercover-Einheit befördert, um Villanelle, eine Auftragskillerin, zu verhaften um an ihre Auftraggeber zu gelangen. So entwickelt sich der Fall zu einem epischen Katz-und-Maus-Spiel zwischen den beiden hochintelligenten, aber auch besessenen Frauen.
In 1945, as the War of Resistance Against Japan comes to an end, the Japanese army secretly transports a large quantity of poison gas bombs to China. Ou Xiao’an, the ace special agent of the military, is injured while escaping from the "810" poison gas research institute. He is inadvertently rescued by Tan Moqing, another agent. When he wakes up, he discovers that he has lost nearly four years of memory. As they work together to expose the Japanese conspiracy, Ou Xiao’an and Tan Moqing frequently join forces, ultimately unveiling the identities of the Japanese spies while also revealing their own roles as underground party members. However, a greater crisis looms ahead; they remain unaware of the whereabouts of the "810" research data and the hidden gas bombs. Faced with numerous dangers and obstacles, how should this group of lonely yet brave individuals advance and fight courageously?
In Montreal in 1945, a few months after the end of the Second World War, Jean Thibault, aka IXE-13, Canada's top secret service agent, is now the respected owner of the Crystal Club in Red Light and a former hotel above the club that once belonged to the Mafia.