20世纪20年代，俄克拉荷马牧场主威廉·霍尔（罗伯特·德尼罗 饰）因为地方上新发现石油资源的缘故，阴谋策划要将周边印第安土著部落的头人一网打尽，好独占这无尽的财富。结果引来了联邦调查局特工汤姆·怀特（杰西·普莱蒙 饰）的注意，而霍尔娶的印第安姑娘的侄子布克哈特（莱昂纳多·迪卡普里奥 饰）成了重点调查的对象 。
故事发生在美国西部大开发时期，燕西（理查德·迪克斯 Richard Dix 饰）带着妻子莎布拉（艾琳·邓恩 Irene Dunne 饰）千里昭昭来到了广袤而又荒芜的俄克纳马拉，心里怀揣着远大的理想，希望能够在这里做出一番建树。俄克纳马拉的生活环境十分艰苦和险峻，然而，夫妻两人同心协力，慢慢改善和建立着他们的家园。在日子渐渐稳定的过程中，在当地生活的牧场主们感到他们的利益受到了侵犯，他们常常会找燕西的麻烦，却又被燕西用智慧巧妙的化解。燕西十分同情在当地生活的印第安土著，与此同时，嫉恶如仇的燕西亦对压迫和剥削原住民的资本家们充满了仇恨，随着时间的推移，双方的矛盾渐渐尖锐起来。
A lost film based on the 'Reign of Terror', a real-life series of several dozen murders committed against the Osage people. 'Tragedies of the Osage Hills' was directed by James Young Deer, the first known Native American film director, and boasted a cast of “hundreds of real Indians.” Described as a dramatic thriller interwoven with a “tender love story”, the film’s premiere in Cushing, Oklahoma occurred just months after the arrest of Ernest Burkhart, the subject of Martin Scorsese’s similarly themed 2023 film 'Killers of the Flower Moon'. The 'Cushing Daily Citizen' described 'Tragedies of the Osage Hills' as having a fictitious ending of the Osage and white men united under an American flag.
Rod Cameron stars as frontier scout Tim Clay, assigned to guide a wagon train through Indian territory. Clay knows that he's in for a lot of trouble because of the treaty-violating activities of white criminals Pickett and Keane. Fortunately for the hero, Pickett and Keane double-cross each other somewhere along the line, weakening their ability to foment an all-out Indian attack.
From great plains of Oklahoma to mountains in south west of France, two native cultures match each other. Two women talk about their culture, their threatened language. Isabelle from France in the Osage country, Chelsea from the Osage country in France.