在天主教教會歷史上的關鍵轉捩點，教宗本篤十六世與承繼的方濟各教宗發展出令人意外的友誼。本片改編自真人實事。

Cardinal Lawrence is tasked with leading one of the world's most secretive and ancient events, selecting a new Pope. Once the Catholic Church’s most powerful leaders have gathered from around the world and are locked together in the Vatican halls, Lawrence finds himself at the center of a conspiracy and discovers a secret that could shake the very foundation of The Church.

In 1458, five years after the fall of Constantinople to the Turk, eighteen cardinals meet to elect a new pope. Rodrigo Borgia, a 27 year old cardinal learns to play a very dangerous game.