원인을 알 수 없는 미스터리 현상들이 뉴욕의 곳곳에서 발생되고, 사람들이 계속해서 스스로 목숨을 끊는 사태가 벌어진다. 이러한 엄청난 사태가 속출되자 모든 학교들이 임시 휴교에 돌입하고 뉴욕에는 대피령이 내려진다. 고등학교 과학 선생님인 엘리엇(마크 윌버그)은 정체 불명의 미스터리 현상들로부터 도망치기 위해 부인 알마(주이 디샤넬)와 수학 선생님 줄리앙(존 레귀자모), 그리고 그의 8살난 딸 제스(에슐린 산체스)와 함께 기차를 타고 펜실베니아의 시골로 향한다. 그러나 이 끔찍한 사건들은 뉴욕 뿐만 아니라 필라델피아, 뉴잉글랜드, 메사추세츠, 메릴란드를 시작으로 전 세계로 확산되고, 기차 안 사람들의 공포와 불안감 또한 극도로 커져만 간다. 그러던 중 갑자기 기차의 모든 시스템이 중단되고, 세상 모두와 연락이 끊긴 것을 알아챈 엘리엇은 어느 누구도, 어느 곳도 안전하지 못하다는 것을 깨닫게 된다. 과연 이들이 두려워 하는 것은 무엇인가? 인류는 이러한 극한 상황에서 벗어날 수 있을 것인가?
When terrorist action releases a secret government virus in the Houston Federal building, the employees become aggressive and homicidal. Federal officials quarantine the building to wipe out the infected and control the story, but a small group of uninfected are fighting to get out.
Unraveling one of the biggest environmental scandals of our time, a group of citizens in West Virginia take on a powerful corporation after they discover it has knowingly been dumping a toxic chemical — now found in the blood of 99.7% of Americans — into the local drinking water supply.
Calvin and Iris's dream vacation turns into a nightmare when a satellite the government claimed to have destroyed crashes near their campsite and releases a deadly toxic cloud.
A nature field researcher is investigating the strange extinction of small animals and insects in the area, which indicates that something is wrong. His suspicions are soon to be proven right when he meets May, who lives in a cabin in the forest nearby. May says that her house is infested by small creatures that she thinks are mice or rats. When the couple search the house further, they notice that they're not rodents or insects. They are fast evolving lizards that have the appetite for animals and humans, no matter what size their prey are...
Marcus, an average young man awakens to find his apartment under quarantine and completely isolated from the outside world. Ominous messages about toxins and evacuations plaster each screen of his various electronic devices, leaving his next door neighbor as the only person he has contact with. Scared, and with few resources, the two try to navigate there way through the indefinite wait - staving off hunger, boredom, and paranoia.
Before starting a family, Soozie Eastman, daughter of an industrial chemical distributor, embarks on a journey to find out the levels of toxins in her body and explores if there is anything she or anyone else can do to change them. She has just learned that hundreds of synthetic toxins are now found in every baby born in America and the government and chemical corporations are doing little to protect citizens and consumers. With guidance from world-renowned physicians and environmental leaders, interviews with scientists and politicians, and stories of everyday Americans, Soozie uncovers how we got to be so overloaded with chemicals and if there is anything we can do to take control of our exposure.