Shōtarō Tatewaki is a normal high school student with a serious demeanor hangs around with Sakurako Kujō. Sakurako is an extraordinarily beautiful woman in her mid-20s from a rich family who loves "beautiful bones." The two live in the city of Asahikawa in Hokkaido, and they get involved in various incidents regarding bones.

Born in an affluent family, Sakurako is grown beautiful but rather spirited and speaks roughly. As an osteologist, she reconstructs skeletal remains of animals in her atelier at home when receiving job offers from museums. Deeply inspired by the beauty and majesty of bodies, her eccentricity is remarkable. "Dead bodies speak eloquently." says Sakurako, at the events of examining incidents. She observes bodies and the crime scenes very carefully, and reveals the truth one by one. Kujo Sakurako, the beautiful osteologist, resolves the cases with her expertise hearing the "voice" of bones. How does this extraordinary heroine resolve cases?