Akira Fudo aprann nan moun pou li yo pi bon zanmi Ryo Asuka ke demòn yo pral vin nan lavi ak reklamasyon nan mond lan nan moun yo. Ak moun pa gen espwa nan sa a divilgasyon, Ryo suggere konbine ak yon demòn. Ak sa a, Akira vin Devilman, yon moun k ap gen pouvwa nan demòn nan men yon moun k ap gen kè nan moun.

Determined to protect his demon world from heavenly angels, demon Masatora Akutsu heads to earth in search of a charismatic human to rally his kin. Masquerading as a high schooler for his recruitment mission, he's captivated by the lovely Lily Amane. But he's in for a wild celestial surprise, because she's his archnemesis—an angel—and she's set on reforming his demonic ways!

A new guardian "angelus" uncovers a secret behind the Angelus System's bureaucracy that leads him to break its official rules about protecting humans.