設於首集超過十年後，成為納美人並與奈蒂莉共結連理的傑克，在潘朵拉星上與他們的孩子組成蘇里一家，過著與世無爭的幸福生活，未料威脅再度降臨，他們不遺餘力保護彼此，為了生存再度奮戰，還得承受隨之而來的悲痛創傷。
根據馬雅預言，我們所生存的地球，是在所謂的第５太陽紀，到目前為止，地球已經過了四個太陽紀，而在每一紀結束時，都會上演一齣齣驚心動魄的毀滅劇情，以現今西曆對照這個終結日子，就在西元２０１２年１２月２２日前後。 2009年，科學菁英團隊向美國總統證實，地球即將在2012年毀滅。因此，世界各國首領緊急研議各種可能計畫，希望挽救大多數人類的生命，然而，並非所有人都能幸運獲救。當男主角傑克森〈約翰庫薩克 飾演〉帶著他的兩個小孩前往黃石公園旅遊時，竟意外發現在乾涸的湖床底下有個秘密的科學研究機構，而裡頭藏著政府一直試圖隱瞞的末日震撼秘密。
由於新冠肺炎大流行，許多公司要求員工居家上班，人與人之間的交流大幅減少。海莉與幾個要好的朋友決定每周舉行一次視訊通話，以維持彼此間的感情。這次的視訊，他們決定變個花樣召喚靈魂問問題，只是…請魂容易送魂難，在這場視訊中的所有人，都將面對惡靈的入侵…
本片所有場景幾乎都發生在一個小房間內，講述11名陪審團如何在另一名持反對意見的陪審團的說服下放棄成見，以挽救一條性命。 故事背景設定在1950年的美國紐約，一名在平民窟長大的西班牙裔美國少年，被控以彈弓刀殺死自己的親生父親，案發時目擊者和證物鐵證如山，少年將被處以一級謀殺的死刑。擔任此案的12名陪審團結案前在休息室商議案情，皆對此案不削一顧，認定少年一定是殺人兇手，只有8號陪審員，針對案情疑點逐一申論擊破，最後獲得其他陪審員的認同，進而扭轉裁判。
本片一片的時空背景設定在西元2415年，故事描繪一個令人震驚的未來世界。當政府幹員謀殺了她的家人，伊恩芙拉斯（莎莉塞隆飾）發誓要報仇雪恨。她成為一名受過嚴格訓練，負責在最前線執行危險任務，對抗一個表面上看起來完美無缺的社會，因為只有像伊恩這種少數人才知道，這個完美社會和人人過的完美生活，底下其實隱藏著一個大謊言。 電影改編自鍾彼得（Peter Chung）編導的同名動畫作品，1991～1995年在美國MTV播映的。
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Ever had a good experience with doorstep salespeople? Maybe you were lucky, but the doorstep has never seemed the best place for a sensible sales decision – which is exactly why companies use it.