Bartleby Gaines (Justin Long) não é aprovado em nenhuma universidade e, para evitar a decepção dos pais, inventa um convite do fictício South Harmon Institute of Technology (S.H.I.T.). Seus amigos igualmente recusados também fazem uso da criação, mas a coisa fica séria quando os responsáveis passam a exigir maiores informações sobre o instituto. Determinado a levar a farsa adiante, o grupo se apropria de uma clínica abandonada, que logo é invadida por dezenas de estudantes reprovados.

A re-edited version of Mario Bava's "Lisa and the Devil" for the U.S. market, including newly filmed scenes involving a possessed Lisa.

In a world where sorcery and science co-exist, the power of magic comes with a price: Humans who do not take proper precautions are transformed into horrific demons. Those who destroy these demons - and run the highest risk of all - are tactical sorcerists known as Strait Jackets.

Howard is mild-mannered and slightly simple-minded, with a habit of picking up teenage hitchhikers while driving his delivery routes. Sometimes the girls admit to being runaways, and if they claim to hate their mothers it drives Howard into a violent frenzy; his sister ran away from home years ago and was never heard from again, causing his desperate, addled mother to tighten her hold on him. Howard never remembers raping his victims or strangling them with wire coat hangers, though his boss does notice missed deliveries and late arrivals.