Krustvārdu mīklu sastādītāja Marija Horovica ir gudra un skaista, bet tajā pašā laikā īsta katastrofa, kura caur caurēm satricina kinooperatoru Stīvu. Marija uzskata, ka jūtu ķīmija, kas radusies aklā randiņa laikā ar Stīvu, ir nenoliedzama, tādēļ viņa uzskata, ka beidzot ir atradusi savu dvēseles radinieku. Viņa ir nolēmusi darīt it visu un doties ar kopā ar Stīvu jebkur, cerot viņu pārliecināt, ka viņi abi sader kopā.

For Dan Gallagher, life is good. He is on the rise at his New York law firm, is happily married to his wife, Beth, and has a loving daughter. But, after a casual fling with a sultry book editor named Alex, everything changes. Jilted by Dan, Alex becomes unstable, her behavior escalating from aggressive pursuit to obsessive stalking. Dan realizes that his main problem is not hiding his affair, but rather saving himself and his family.

As she reaches her mid-thirties and quits her lucrative job, singleton Olivia finds herself unsure about her future and her relationships with her successful and wealthy friends. She begins to envy the security of her richer friends and, although their lives may seem easier, Olivia's friends have their problems too: screenwriters Christine and Patrick are unable to collaborate on their latest project, Jane and Aaron have lost the romance in their relationship, and Franny and Matt have difficulties handling the demands of parenthood.