When cops Schmidt and Jenko join the secret Jump Street unit, they use their youthful appearances to go under cover as high-school students. They trade in their guns and badges for backpacks, and set out to shut down a dangerous drug ring. But, as time goes on, Schmidt and Jenko discover that high school is nothing like it was just a few years earlier -- and, what's more, they must again confront the teenage terror and anxiety they thought they had left behind.

Simon and Robyn are a young married couple whose life is going as planned until a chance run-in with Simon's high school acquaintance sends their world into a tailspin.

Angela Delvecchio, coming from a rather poor family, moves into the rich town Montevista. She admires Stacy, leader of the most prestigeous clique of her high school. Angela wants to be accepted and seeks Stacy's friendship. But when she defends outsider Monica against Stacy, she becomes Stacy's target herself. Mocked, she stabs Stacy with a kitchen's knife. The trial becomes a sensation.

Socialite Molly Lasch is released from prison after serving a six-year sentence for the murder of her husband, Dr. Gary Lasch. Now, with the help of Fran, an investigative reporter, Molly sets out to prove her innocence. Together they uncover a conspiracy of silence at the Lasch Medical Center and a shocking secret that could cost both women their lives.