對魔法感到憧憬的人類少女阿麗斯，有一日來到了魔法世界。在那裡，她邂逅了實習魔女舒拉和艾華，並對所有事物充滿好奇。然而這世界並非她所想像的美好，恣意捕捉妖精、魔女與魔族間的對戰以及魔法界與魔導書的秘密，將一一在阿麗斯的眼前呈現……

In the near future, massive hostile beings called "Fiarem" are waging war on Earth. To defend the world from this alien threat, Japan unleashes a special team known as "Ragna Strikers"—six young women wielding advanced weaponry and the ability to grow to gigantic sizes. Ragnastrike Angels follows Ayano Anemori and her friends as they live their daily lives and battle the violent Fiarem.