Inspired by the fictional Dr. Heiter, disturbed loner Martin dreams of creating a 12-person centipede and sets out to realize his sick fantasy.

Hanna secretly joins a group called The Onania Club. Its members, strong independent L.A. women, get aroused by the misery of others. Hanna meets more misery than she could ever hope for and in the process loses everything she cares for.

Jero is a sex and masturbation addict who, due to his own body being alerted to so much excess, joins a group of addicts. As the group does not help him overcome his problem, he takes refuge in religion, where he will have to face other types of demons.