Charlie Hudson nyomozó a St. John's-i rendőrség bűnügyi csoportjánál dolgozik hű társával, az egykori K-9-es németjuhász kutyával, Rexszel. A rátermett törvényszéki nyomozó Sarah-val és az informatikus Jesse-vel együtt a végére járnak minden bűnténynek, legyen az bármilyen bonyolult. Charlie és Rex reggeli kocogásuk során tanúi lesznek, amint elrabolnak egy tinilányt. Rex követi a tetteseket. Miután senki sem jelentette a lánya eltűnését, a nyomozó osztály nehéz helyzetben van, de a meglévő kevés bizonyítékkal és persze Rex segítségével hamar megtalálják a lányt.

The Littlest Hobo is a Canadian television series based upon a 1958 American film of the same name directed by Charles R. Rondeau. The series first aired from 1963 to 1965 in syndication, spanning six seasons and was revived for a popular second run on CTV from October 11, 1979 to March 7, 1985. It starred an ownerless dog.

All three productions revolved around a stray German Shepherd, the titular Hobo, who wanders from town to town, helping people in need. Although the concept was perhaps similar to that of Lassie, the Littlest Hobo's destiny was to befriend those who apparently needed help. Despite the attempts of the many people whom he helped to adopt him, he appeared to prefer to be on his own, and would head off by himself at the end of each episode.

Never actually named on-screen, the dog is often referred to by the name Hobo or by the names given by temporary human companions. Hobo's background is also unexplained on-screen. His origins, motivation and ultimate destination are also never explained.

Although some characters appeared in more than one episode, the only constant was the Littlest Hobo himself.

The Adventures of Rin Tin Tin is an American children's television program. Beginning in October 1954 until May 1959, 166 episodes originally aired on ABC television network. It starred child actor Lee Aaker as Rusty, a boy orphaned in an Indian raid, who was being raised by the soldiers at a US Cavalry post known as Fort Apache. He and his German shepherd dog, Rin Tin Tin, helped the soldiers to establish order in the American West. Texas-born actor James Brown appeared as Lieutenant Ripley "Rip" Masters. Co-stars included veteran actor Joe Sawyer and actor Rand Brooks from Gone with the Wind fame.

Run, Joe, Run was a Saturday morning television program that aired on NBC from 1974 to 1976. It centered around Joe, a German Shepherd in the military's K-9 Corp., and his master, Sergeant Will Corey. One day, during training, Joe was falsely accused of attacking his master, a crime for which the dog would be put to sleep as punishment. However, he escaped before being killed and a $200 bounty was put on his head.

Sgt. Corey believed Joe was innocent and also pursued him, hoping to find Joe before the authorities did. While on the run, Joe helped people he encountered.

During the show's second season, Sgt. Corey, having never found Joe, was called back to duty. Joe then teamed with a hiker, Josh McCoy, and continued to help others, all the while still on the run.

The show was considered as a cross between Lassie and The Fugitive. Like The Fugitive, and later, The Incredible Hulk, it centered around a falsely accused person running from authorities and helping out people he meets along the way. The show was produced by William P. D'Angelo Productions, who also produced the NBC young adult drama, Westwind.

A German Shepherd roams ceaselessly, pausing solely to perform acts of kindness or assist those in distress, before resuming his never-ending journey.

Kelly is a Australian children's television series that first screened on Network Ten in 1991. The series was produced by Jonathan M. Shiff Productions and featured the adventures of a former highly trained German Shepherd police dog called Kelly.