Amelie har haft en trist barndom uden kærlighed og arbejder nu som tjener. Hun har en romantisk og fantasifuld natur, og en dag beslutter hun sig for fremover at gribe ind i andre menneskers liv for at bringe lykke og glæde. De bringer hende i kontakt med en lang række mennesker, heriblandt den hypokondriske Georgette, den aldrende og skrøbelige kunstner Dufayel og den ensomme Nino, der er ekspedient i en videoforretning.
Skye, en kæk teenager med en dødelig sygdom, og Calvin, en 19 år gammel hypokonder, der er bange for sin egen skygge, møder hinanden. Calvin hjælper Skye med at fuldføre sin excentriske "træskoliste" over ting, hun skal nå, inden hun dør. Undervejs lærer han at konfrontere og overvinde sin egen frygt - blandet andet frygten for at forelske sig i den smukke, men tilsyneladende uopnåelige Izzy.
Quinn, a neurotic man, is diagnosed with a harmless eye condition and soon after his life spirals out of control. He second-guesses his plans to propose to his longtime girlfriend, Devon, after his beautiful coworker, Kelsey, confesses that she has a crush on him. After a conversation with his best friend, Jameson, he clumsily tries to explain his doubts to Devon, but his possible proposal turns into a break-up. When Devon flees to Paris, he follows her in a last-ditch effort to win back "the one."
Kassie vil gerne have et barn, men der er ikke nogen mand i hendes liv. Wally vil gerne være manden i Kassie’s liv, men Kassie er ikke interesseret. Kassie beslutter at lade sig inseminere, og i en brandert sørger Wally for, at det bliver med hans sæd. Det ved Kassie ikke, og næste dag kan Wally intet huske. Men da han syv år senere møder Kassie’s søn, er der et eller andet ved knægten, der virker bekendt.
Fascinated by his friend's success abroad, an out-of-work barber Šurda tries his luck in Germany. Incapable to accept any job that would suit him, he returns to his homeland in disappointment. Based on a popular TV serial "Hot Wind" ("Vruć vetar").
Hannah's eksmand tror, han skal dø. Hannahs mand er forelsket i hendes søster Barbara. Hannah's to andre søstre vil låne penge af hende til deres nye catering-firma. Hannah skal sørge for Thanksgiving-middag til hele familien. Hannah ville have det en hel del lettere uden søstre samt tidligere og nuværende mænd.
Norman Jewison har instrueret et af Hollywoods mest berømte filmpar, Doris Day og Rock Hudson, som en munter hustru og hendes hypokondriske mand i denne film, som var deres tredje og sidste sammen. Hudson er vanvittigt morsom som en besat hypokonder, der kommer til at overhøre sin læge tale om en patients nært forestående død. I den tro at det er ham selv, går Hudson og en ven (Tony Randall) i gang med at finde en ny mand til hans kone, som jo snart bliver enke. Randall er desværre ikke nogen stor hjælp, fordi det forestående tab får ham til at drikke. Day bliver foruroliget over sin mands opførsel, og det bliver endnu værre, da en gammel flamme (Clint Walker) dukker op i deres country club og Hudson opmuntrer ham til at gøre tilnærmelser til hende!
A gang of thieves plan to make their fortune by stealing a shipment of contraceptive pills from Finisham maternity hospital. They assume disguises and infiltrate the hospital, but everything doesn't go according to plan. The hypochondriac consultant Sir Bernard Cutting, Matron and the doctors and nurses at Finisham have a habit of getting in the way.
Romain Faubert is a 39 year old, single, medical photographer... and a raging hypochondriac. His doctor and only friend Dr. Dimitri Zvenka thinks he knows the cure for Romain: dating! But with the arrival of freedom fighter Anton Miroslav, everyone might get more then they bargained for...
Young boxer Michel Maudet is sacked by his manager after a series of match defeats and is forced to look for a new job. He is engaged as secretary to a millionaire named Ferchaux who is in a hurry to flee the country when he discovers he has been implicated in a high-profile fraud.
A small town doctor mistakenly ingests an experimental drug made from the blood of vampire bats which transforms the kindly medic into a bloodthirsty monster.
The sexual relationship between a successful woman and her brother, an introvert, hypochondriacal youth, who is also a pornophile.
Odile is a business executive looking for a new, bigger apartment. Her younger sister Camille has just completed her doctoral thesis in history and is a Paris tour guide. Simon is a regular on Camille's tours because he's attracted to her. Camille has fallen for Marc, and they begin an affair. Nicolas is also looking for an apartment, since he hopes to eventually have his family join him in Paris.
Dr. Steven Bishop is taken to the hideout of Frank Dillon and his gang to treat the wounded Joe Madison. Joe's nurse sister Nora Madison is also taken. Dillon tells Bishop that if Joe dies, he will be killed, but Bishop knows he will be either way. Joe dies, but Nora and Steve conceal it from Dillon and send a plea for help in a prescription that Bishop writes in Latin.
Sometimes he feels a tugging in his shoulder, sometimes he thinks his kidneys are failing. Two weeks before his marriage to the beautiful Anne, junior architect Stefan seems to have gathered all the diseases in the world. Drawn from the stress of the wedding preparations, the hypochondriac is in top form. When he overhears a phone call from the family doctor, he mistakenly thinks he is a dead man. Now a substitute husband is needed for Anne.
Horrifying certainty about the date of his death drives one man crazy.
Donald's got the day off, and all he can think of is golf until it rains as soon as he sets foot outside. He takes it out on his nephews. When he's sitting around moping, they take revenge by playing off his hypochondria.
When his best friend dies of a heart attack, Ray Macklin becomes a man obsessed with his own mortality. Convinced that all his aches and pains are an indication of his imminent death, Ray's life turns into a slapstick farce of health-crazed anxiety and hypochondria.
Tucked away in his castle, a hypochondriac inventor plays generous host to a revolving cast of wacky guests. But to pay off his mounting debts, he must sell either a powerful businessman or a rich gypsy on his latest creation: a laser skywriter.