John Ryan titkosügynököt akarata ellenére főnöke ideiglenesen saját helyére előlépteti, ám hamarosan hálátlannak bizonyul politikai körökben. A kolumbiai drogkartellekre irányuló nyomozásai során bizonyos szálak egészen a Fehér Házig vezetnek. Az elnök egyik befolyásos barátja az összekötő kapocs. Ryan körül furcsa dolgok történnek, a főnöki szék egyáltalán nem életbiztosítás számára. Kolumbiába küldik, ahol merényletet kísérelnek meg ellene. Egy idő után összemosódik a barát és az ellenség fogalma.
In the crime world of Colombia, there is an unwritten code. When Víctor and Eusebio, two hoods who bungle a shake-down job, break that code, they unwittingly sign their own death sentence.
A miserable Argentine troupe of actors, dancers, musicians, filmmakers and a girl embark on a theatre tour to some country, probably in Latin America.
Marc, an unexperienced medical doctor from Germany arrives at the Hospital Universitario del Valle in Cali, Colombia for his internship and soon finds himself in-between a raging gang war in Siloé, a Cali barrio. In the hospital he has to care mostly for shotgun wounds, while in the streets he falls in love with a stall-holder who cares for some of the children involved in drug trafficking and criminal violence. Alienating his colleagues and his host family while befriending the kids, he soon finds himself trapped in the center of the violent conflict between the gangs and has to come to a decision.
A young boy is forced by his father to kill a horse. As night falls, in shock, the lights flicker and the television displays disturbing images, the boy is drawn to a mysterious light. In a supernatural encounter, his reality fades away.