Born in Lausanne from a father of Spanish origin and a mother of German origin, Vincent Pérez (Vicente Pérez) spent a good part of his childhood in Penthaz and then in Cheseaux, Canton of Vaud. After studying photography at the Center Doret in Vevey, he studied dramatic art in Geneva, then at the Conservatoire and the school of Amandiers de Nanterre.

Vincent Pérez in 1991, at the 16th César ceremony. He is still a student when he begins the movie in 1985 in the Guardian of the Night. It is in 1990 that it imposes to the international level playing in Cyrano de Bergerac. He is quoted to the César of the best male hope. In 1991, it is found in Indochina, winner of the Oscar for the best film in foreign language. In the same year he won the Prix Jean-Gabin. Since then, he plays characters of romantic lovers in La Reine Margot, Fanfan, films that allow him to rub shoulders with major French actors. He subsequently plays in some thirty European or American films. He is quoted to the César for best actor in a supporting role 1998 for his interpretation in the Hunchback and the following year for Those who love me will take the train.

Vincent Pérez at the 2000 Cannes Film Festival. In 1992, he made his directorial debut with the short film "L'échange", nominated for the Jury Prize for short films in Cannes. He returned behind the camera in 1999 to realize "Rien dire" also cited in Cannes. In 2002, he made his first feature film Peau d'Ange, of which he is co-writer. He is the author of the script for La Forêt, a comic strip he makes with the renowned author Tiburce Oger, who revisits the myth of the forest of Brocéliande. In 2007, he realized Si j'étais toi produced by EuropaCorp. He is married to Karine Silla and had three children with her: Iman, May 2, 1999, and the twins Pablo and Tess in 2003. He is the father-in-law of Roxanne Depardieu, the fruit of the union of Karine Silla and Gerard Depardieu. He shared the life of Jacqueline Bisset then Carla Bruni-Sarkozy at the beginning of his career. In 2009, he participated in the song "Beds are burning", collective for the Copenhagen conference. In 2010, he was chosen alongside Virginie Ledoyen as a muse for the IKKS brand. His sister, who still lives in Switzerland, has made and marketed original hats that have had some success. Described [relevance challenged] In 2012, he publicly supports Chief Raoni in his fight against the Belo Monte Dam. Has manufactured and marketed original hats that have had some success. Described [relevance challenged] In 2012, he publicly supports Chief Raoni in his fight against the Belo Monte Dam. Has manufactured and marketed original hats that have had some success. Described [relevance challenged] In 2012, he publicly supports Chief Raoni in his fight against the Belo Monte Dam.

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Né en Suisse à Lausanne, Vincent Perez (à l'état civil Vicente Pérez) est le deuxième des trois enfants d'Antonio Pérez Alberola, d'origine espagnole, qui a immigré en France pour venir travailler dans l'import-export, et d'Arnoldine Bush, d'origine allemande, née le 30 juin 1939 à Bonn. Son grand-père paternel Antonio Pérez Picot a été fusillé par les franquistes en 1939. Vincent Perez passe une bonne partie de son enfance à Penthaz, puis à Cheseaux-sur-Lausanne, dans le canton de Vaud.

Après des études de photographie au Centre d'enseignement professionnel de Vevey, il étudie l'art dramatique à Genève, puis au Conservatoire national supérieur d'art dramatique de Paris et à l'école des Amandiers de Nanterre.

Il est encore étudiant lorsqu'il débute au cinéma en 1985 dans Gardien de la nuit. Dès ses débuts d'acteur, il est courtisé par les plus grands réalisateurs : Patrice Chéreau (Hôtel de France), Jean-Paul Rappeneau (Cyrano de Bergerac) ou encore Ettore Scola (Le Voyage du capitaine Fracasse). En 1992, Indochine de Régis Wargnier lui permet d'asseoir son statut de séducteur. Dès lors, Vincent Perez va collectionner les personnages d'amants romantiques, que ce soit dans des comédies (Fanfan, Le Libertin, Epouse-moi) ou des fresques d'envergure (La Reine Margot).

C'est à partir de 1996, avec Par-delà les nuages de Michelangelo Antonioni et Wim Wenders et The Crow : la cité des anges, que le comédien donne une orientation internationale à sa carrière. Cette tendance se confirme avec Au coeur de la tourmente (1997), un drame sentimental où Vincent Perez a pour partenaire Rachel Weisz, Je rêvais de l'Afrique (2000), où il s'éprend cette fois-ci de Kim Basinger, ou encore La Reine des damnés (2002) qui lui permet de renouer avec le genre fantastique. Souhaitant casser son image de jeune premier, l'acteur n'hésite pas à s'illustrer en traître dans Le Bossu (1997) et à se travestir dans Ceux qui m'aiment prendront le train (1998), prestations qui lui vaudront d'être nommé à deux reprises pour le César du Meilleur second rôle.