Radha Blank (born September 1, 1976) is an American filmmaker, writer, and actress. Born and raised in New York City, Blank is known for writing, directing, producing, and starring in the critically acclaimed feature film The 40-Year-Old Version.

Blank got her start in the TV and film industry as an actress playing the role of Loquesha in the 1998 film Mixing Nia. She began her writing career as a playwright, writing several plays that never made it to the stage and the Off Broadway production Seed which received critical acclaim. Blank has performed as a comedian and rapper under the name RadhaMUSprime.

For her directorial feature debut, The 40-Year-Old Version, Blank won the 2020 Sundance U.S. Dramatic Competition Directing Award and the Gotham Independent Film Award for Best Screenplay. Her other accolades include a Helen Merrill Playwriting Award, an NEA New Play Development Award, the Sundance Institute's 2020 Vanguard Award, and a NYFA Fellowship.