Pamela Koffler is an American film and television producer and founding partner of Killer Films, an independent New York-based production company she co-leads with Christine Vachon.

Koffler has produced a large body of critically acclaimed and award-winning films and television series, including Hedwig and the Angry Inch, Mildred Pierce, The Velvet Underground, Past Lives, and May December, which premiered in competition at the 2023 Cannes Film Festival and was acquired by Netflix.

Koffler has been nominated for various entertainment awards, including Primetime Emmy Award and PGA Award nominations for Mrs. Harris in 2006 and Mildred Pierce in 2011, a Film Independent Spirit Award nomination for Hedwig and the Angry Inch in 2002 and win for I'm Losing You in 2000, and an IDA Award win for This American Life in 2008.