Detective and family man John Lowe investigates a chain of gruesome murders in Los Angeles. A mysterious tip points him to the enigmatic Hotel Cortez.

Fashion mogul Will Drake brings couture to the Hotel Cortez. A model catches The Countess's eye. John learns about the hotel's sadistic first owner.

Alex is pushed to her breaking point after Scarlett stirs up memories of Holden. Donovan is targeted by a dangerous rival of The Countess.

John receives an invitation to attend an exclusive Devil's Night Soiree. Alex tries to diagnose Holden's strange condition.

Alex uses an unconventional treatment to save a dying patient. A Halloween-hating couple tests Iris’s limits.

Ramona and Donovan enact their plan for revenge. Liz Taylor finds true love. The resident of Room 33 is revealed.

Will Drake’s renovations uncover one of the Hotel’s greatest secrets. John undergoes psychiatric evaluation. The Countess learns the fate of her first love.

The Countess is reunited with her one true love. Donovan and Ramona take another stab at revenge. A careless decision lands Alex in hot water.

Alex enlists John's help to contain an outbreak. Donovan learns the Countess' true intentions. Liz and Iris plan to leave the hotel for good.

Ramona draws vitality from an unlikely source. Sally uses her past to negotiate her future. Scarlett learns the truth of her family's affliction.

Iris and Liz oversee a new era at the Cortez. John and Alex struggle to adapt to life outside the hotel.