BrainSurge is an American children's game show aired on Nickelodeon hosted by Jeff Sutphen. The show taped its first season in February 2009, and debuted on September 28, 2009. The show's format was adapted from the Tokyo Broadcasting System game show Brain Survivor.

The network announced on February 18, 2010 that the program was renewed for a second season, that will consist of 40 episodes, and will feature the same format without any known changes. The second season, which featured the 40 original episodes plus one episode held over from season one, premiered on June 21, 2010. The third season started airing on July 18, 2011 on Nick@Nite. Season 3 is marketed as Family BrainSurge, and has a two-person family team format with five teams.

BrainSurge was taped at Hollywood Center Studios in Hollywood, California.