A school bus is abducted by kidnappers who demand more and more for ransom.

När en präst försvinner börjar Jack misstänka att försvinnandet beror på att han varit inblandad i något brottsligt.

A missing-persons case becomes a criminal investigation when, after a recently engaged woman disappears, it turns out that she was running a confidence scheme.

When a 14-year-old violinist disappears on the night of a concert, the team follows her and her valuable violin's trail and Samantha bravely tries to recover from the gunshot wound.

Malone searches for a missing woman whose description matches those of a series of murder victims from a 12-year-old case only to learn that Graham Spaulding is pulling the strings, and drawing on incidents in Jack's past to lure him into a trap.

When a high school sex-scandal leads to murder it is the team's job to figure out who did it and why.

En oidentifierad ung spansktalande pojke kidnappas och teamet upptäcker att pojken kan ha förföljts av en pedofil som nyligen flyttat in i grannskapet.

Teamet söker efter en brandman som försvann efter att ha räddat livet på sina kollegor.

Jack och hans kollegor söker efter en neurokirurg som försvunnit spårlöst efter att hon varit ute och joggat med sin före detta man.

Teamet söker efter en man som försvunnit efter en skolåterförening.

Jack och teamet letar efter en paparazzo som försvunnit från en kändisfotografering, och hans kamera hittas täckt av blod.

Teamet söker efter en motivationstalare som blev kidnappad när han var på väg till flygplatsen.

Teamet söker efter en före detta polis som sadlat om till prisjägare och försvunnit efter att han blev skjuten.

Teamet söker efter en tolvårig pojke som försvunnit från sin skola.

A new lead reveals details about a missing woman's sexual history.

Jack och Danny söker efter den saknade soldaten Kevin. Jack upptäcker att Kevin haft ekonomiska problem och åker till Irak för att ta reda på sanningen.

The team searches for a man who goes missing after leaving his wife's hair salon to deposit the day's earnings following an argument with her. Meanwhile, Danny resists getting pulled back into the life of his convict brother who is up for parole, and Martin's impending firearms qualifications test dredges up unsettling memories for him.

The team investigates a missing woman's boyfriend, with whom she lived. However, they determine that he has a twin brother and quickly turn their attention to him.

When Sam helps Martin search for his missing and terminally-ill aunt, they discover that she's been using her nursing skills to assist other dying patients in committing suicide; his father's Alzheimer's diagnosis prompts Jack to attempt a reconciliation.

When a father who goes missing while trying to prove that his son a death-row inmate who is scheduled to die in two days is innocence, The past 11 years of the missing Mans life have been devoted to proving that his son, was wrongly convicted of killing a young married couple in front of their daughter during a convenience story robbery. While the team does not rule out that the despondent man could have brought harm upon himself, the team members find themselves wondering if the man is right about his son innocence.

The team Looks for a college football coach who goes missing after being fired for his role in the team's dismal season performance,but the investigation soon uncovers that the Coach new policy of suspending players who have academic and behavioral issues caused the football team to repeatedly play without its main players and suffer defeats due to this rule. As a result of this, The team begin to suspect that it was some of the angry players, or members of the school administration and even a high-stakes gambler who all are facing financial losses resulting from the teams losing streak. Meanwhile, Malone must make a difficult decision when his wife surprises him with her strong desire to relocate their family to Chicago, where she has just been offered a superb job opportunity

When the team searches whether foul play was involved in the adoption of a 16-year-old girl who went missing back in 1991 shows up at the FBI offices with an article she found online, which makes her believe she was kidnapped as a young child. Meanwhile, Jack tells the team he's moving to Chicago with his family.

The team searches for a mother and her two children, who are last seen boarding a yacht which is later found adrift in New York's Harbor with only its dead captain aboard. Meanwhile, Malone gets ready to leave the team and move with his family to Chicago.