Host Tyler Florence welcomes nine food trucks to the NASA Johnson Space Center in Houston, Texas, where their epic nine-city road trip for $50,000 across America's Gulf Coast begins. These first-time food truck teams face daunting challenges in the hopes of reaping unprecedented rewards, including award medals that have carryover value in the next city. Tyler groups the teams into squads who must scrap for sales in an all-out selling frenzy, and the bottom two teams must face a first time ever shocker of an elimination.

Host Tyler Florence shakes things up in Lake Charles, La., when he tells the teams to plunder one another's food trucks for a challenge judged by a band of hungry foodie pirates. Thousands of customers swarm the trucks, stressing one team to point of implosion and propelling another team to new heights.

Tyler Florence brings the teams into Biloxi, Mississippi, where they hope to rack up some big sales. One team struggles to stay together and comes back stronger than ever, while another team that was previously on top plummets to the bottom two. Though sales start booming, none of the teams are prepared for the backlash when they're accused of price gouging.

Tyler Florence brings in All Elite Wrestling tag teams The Acclaimed and The Gunns to join the food trucks in Pascagoula, Mississippi, for an all-out brawl. One team thinks they're being clever by sitting out on Tyler's challenge, but they soon come to regret their choices.

Four teams meet up with Tyler Florence in Mobile, Alabama, hoping to sell to the massive Mardi Gras crowds lining the streets, but they soon find it's not as easy as it looks. Then, one team accuses another team of cheating, and instead of earning them brownie points, their accusation backfires in unexpected ways.

Three teams pounce on Panama City, Florida, in an effort to scrap their way into the finale. Tyler Florence launches a secret challenge that earns one truck a jaw-dropping advantage against a team of their choosing, and hard feelings from the past may come to play in the present.

Two food truck finalists join Tyler Florence for the final leg in Fort Meyers, Florida, where they feed their fans on a day of intense selling and challenges. Then at the South Beach Wine & Food Festival in Miami, the teams' ultimate fate will be determined, and the winner will claim $50,000 and the title of Great Food Truck Race champion.