Hiro, a young, timid boy, dies while saving a girl on the street from falling construction beams. That girl turns out to be Hime, his sister's new employer, who by resurrecting Hiro makes him into her servant.

With Hiro's life force fading and needing restoration, he slowly comes to realize that he has no choice but to be involved with Hime. As an invisible man enters the mansion to assassinate Hime, she goes wild with a chainsaw chasing him, and eventually even sets the mansion on fire.

Riza, half-sister of the werewolf Lobo Wildman killed by Hime in the first episode, comes to claim her revenge. But she does not yet realize that she herself was used as a chess piece to make Lobo betray Hime.

Hime and company, with Riza in tow, travel to Hime's lake resort and end up being involved with a race of fish men after Hime's immortality powers. Riza declares her intention to stick close to Hime in order to find an opportunity to take her revenge on Hime's brothers.

Reiri, a beautiful vampire girl at Hiro's school, approaches and turns Hiro in order to gain access to Hime's house and obtain her powers by sucking her blood. However, Hime prepares a wide range of countermeasures.

Hime's sister Sherwood shows up one day, proposing an alliance against their other siblings. Hime refuses, but Sherwood's goal from the start was to plant a dangerous man-eating plant near the mansion.

Hiro loses consciousness while shopping and is taken to the hospital. He wakes up there only to be chased by a crazy doctor and his minions. Reiri tells Hime about Hiro's fate and Hime, together with Riza go to rescue him.

Rain, roads blocked by garbage. Hime, Riza and Hiro are forced to stay in the Sasanagi Motel until things are clear. Upon arrival, they find Reiri. But a monster sent by Zeppeli turns things creepier than it should be, except for Hime and Reiri who play chess.

Sherwood seems bored with her arrival at her new mansion since Francisca is missing. Hime tells Hiro to go there and as he reaches it, she meets Francisca carrying a panda. Later on, Sherwood is attacked by monster bats and Hime comes to help.

Hiro finds Hiroko, a cat, by the road and takes her in. Hiroko, actually a cat-person, grows attached to Hiro. She turns out to be an unskilled assassin controlled by the bell on her collar. Shocked by her own behavior, she disappears.

Pharaoh, given the promise of eternal life upon Hime's death, sends his army of mummies to attack Hime. Hime having taken drowsy cold medicine (before knowing about the pending attack) entrusts her life with Hiro.

During a lunar eclipse, Hime and Hiro were pulled into the memory of Akasabi village and had to deal with a serial killer.

Riza has been racing with a ghost knight on Sasanagi Pass. One night, he lost his head and went berserk. Hiro, while helping to search for the knight's head, got kidnapped and turned into Zeppeli's "knight". Hime has to save him.

Hiro's acquaintances find out that he's staying with 3 beautiful women. They confront him and ask Hime if they could be her servants. Hime agrees on condition that they go through an obstacle course in the house. A shape-shifter taking Hiro's form also joins the race to reach Hime first.

Riza, frustrated with training, heads to Hime's lake resort and meets Aron, a were-shark, who was good friends with Lobo Wildman (Riza's brother). Aron turns out to be an assassin of one of the Royalty sent to kill Hime. After being defeated by Riza, she asks Riza to avenge Lobo for her as well.

A witch from the black forest goes after Hime's and Sherwood's spirit to get eternal youth.

A raccoon dog became a vampire hunter in order to feed his family, but mistakenly attacks Hime believing her to be a vampire.

Hime, Hiro and Riza are trapped in a haunted ship and must find and rescue a mysterious mermaid in order to escape. Hime's older brother Emil is introduced.

Hiro is kidnapped by a vampire named Duke Dracul. Riza and Reiri must enter the village of vampires to save him.

Hiro and his friend Buchi visits Reiri after she doesn't come out to school. However, when they get there, Dracul Duke tries to banish Reiri by sending in low-class vampires. Hime's team comes to help.

Hime is attacked by three werewolves at night and she and her team must take them down. Riza fights for her family's pride while Hiro is reminded again that he is a warrior protecting Hime's life.

Hime's team looks for the royalty who sent the werewolves and Dracul Duke. They end up in a town filled with zombies and must get themselves out.

Hime is accused of using zombies by the committee and stands before the judge. She and her brother Severin must battle in order to be freed.

Flandre goes on a rampage and seems to attack anyone that approaches her, including Hime. Guessing that Flandre is self-destructing, the group in vain tries to stop her.

Hime, Hiro, Riza and Reiri are trapped in a nightmare world. They struggle to find a way out of the dream as they are constantly attacked by imaginary enemies.