Serija prati Jedinicu za bihevioralnu analizu koja mora uloviti ubojicu koji je pobjegao iz zatvora s 13 osuđenika na kraju prošle sezone.

J. J. dolazi kući potresena nakon teškog slučaja, slama se i govori mužu o otmici dvoje djece.

Emily Prentiss vraća se u Jedinicu za bihevioralnu analizu kad jedinica mora istražiti nestanak triju žena.

Jedinica za bihevioralnu analizu traži serijskog ubojicu na apalačkoj stazi za planinarenje u ruralnom dijelu Virginije.

Jedinica za bihevioralnu analizu istražuje može li maltretiranje biti veza između dvoje srednjoškolaca koji su jedini preživjeli nakon što su njihove obitelji ubijene.

Kad troje djece nestane vozeći bicikle na istoj stazi na kojoj se dogodio slični neriješeni slučaj prije 30 godina, ekipa stiže kako bi istražila.

Brat stiže u grad i zna sve o njoj i njezinoj obitelji, a ona ne može uspostaviti kontakt sa svojim pravim bratom.

The team heads to Yakima, Washington when the remains of a dozen people are found along a creek bed.

While Rossi conducts a profiling course on his birthday, he receives a call from his nemesis Tommy Yates, who discloses the location of his latest victim.

BAU team investigates a series of home invasions in upscale neighborhoods in San Diego involving casualties.

Reid has returned from Houston, where he was visiting his mother who is in a new facility on an experimental drug program. He is called back home from the office while the rest of the team heads off on their next case. It isn't until the team is in the air that they learn that Diana is no longer in the Houston facility, but that she is now living with Reid, as the trial drug was not having the intended effect.

The BAU team is called in to investigate when male victims are found with no way to identify them.

When a BAU member gets in trouble in Mexico, the team enlists the services of the International Response Team for their help.

The BAU investigates the cause of several fatal car crashes involving drivers and pedestrians. Also, Reid gets bad news.

The BAU investigates when several young men and women are victims of disfiguring acid attacks. Also, Dr. Reid begins to settle into his new surroundings.

When three women in New York City are found dead with several bones broken, the BAU works with a single mother (Tatum O'Neal) who believes that her son is behind the heinous crimes. Meanwhile, Reid faces a difficult decision after a fellow inmate is threatened.

When two drastically different murder sprees are committed in Burlington, Vermont, the BAU concludes that a serial killer suffering from sleepwalking is responsible for both crimes. Meanwhile, Alvez presents Shaw with a shocking ultimatum after Reid is assaulted in prison.

The BAU investigates an urban vampire who kidnaps his victims at night and holds them underground in the sewer system; Reid makes a difficult decision in prison.

Three victims are found tied to stakes in the Arizona desert.

When Reid fears his mother has been abducted, he asks the BAU to investigate while he's stuck in prison.

Derek Morgan brings the BAU a lead in the case against serial killer and escaped convict Mr. Scratch.