Actresses Isabella Rossellini, Anjelica Huston and Mia Farrow explore their family histories, generations beyond their cinematic forebears.

Actors Melissa McCarthy and Eric Stonestreet retrace their ancestral journeys.

Sterling K. Brown, Jon Batiste and Sasheer Zamata learn about the unexpected places their ancestors called home.

The unexpected family trees of Queen Latifah and Jeffrey Wright challenge preconceptions about America's past.

Exploring the Jewish heritages of actor Jeff Goldblum, radio host Terry Gross and comic Marc Maron.

Sigourney Weaver, Justina Machado and Amy Ryan explore their ancestry.

Tracing the family histories of scientists Harold Varmus, Francis Collins and Shirley Ann Jackson.

Questlove, S. Epatha Merkerson and Ava DuVernay explore the unexpected places where their ancestors were scattered by slavery.

Marisa Tomei, Jimmy Kimmel and John Turturro learn about the sacrifices their ancestors made to bring their families from Italy to America.

The family histories of Laura Linney, Lisa Ling and Soledad O'Brien reveal tricksters, scoundrels and criminals.

Guests: Diane von Furstenberg, Narciso Rodriguez, RuPaul. Henry Louis Gates, Jr. steps into the world of fashion and meets three icons of style — Diane Von Furstenberg, Narciso Rodriguez, and RuPaul Charles — introducing ancestors who were just as audacious as they are.

Guests: Téa Leoni, Joe Madison. Henry Louis Gates, Jr. uses DNA detective work to solve mysteries in the family trees of actor Téa Leoni, and radio host Joe Madison, introducing each of them to parents and grandparents whose names they’ve never heard before. (Téa Leoni originally appeared in S04E08. Joe Madison originally appeared in S05E10.)

Guests: Lupita Nyong’o, Lidia Bastianich, Scarlett Johansson. Henry Louis Gates, Jr. meets actors Scarlett Johansson and Lupita Nyong’o, and chef Lidia Bastianich — three women whose families crisscrossed the globe to escape oppression and find opportunity, leaving them with questions about their relatives who stayed behind. (Lupita Nyong’o originally appeared in S04E07. Lidia Bastianich originally appeared is S03E09. Scarlett Johansson originally appeared in S04E05.)

Guests: Gayle King, Jordan Peele, Issa Rae. Henry Louis Gates, Jr. explores the family secrets of journalist Gayle King, film director Jordan Peele, and comedian Issa Rae, introducing them to ancestors who raise profound questions about the shape and meaning of their family trees.

Guests: Nancy Pelosi, Norah O'Donnell, Zac Posen. Henry Louis Gates, Jr. helps Congresswoman Nancy Pelosi, news anchor Norah O’Donnell and fashion designer Zac Posen explore their immigrant roots, retracing the journeys of their ancestors who arrived in the United States with little more than a dream--and revealing why that dream is still so inspiring today.