Bart prende parte a una sfida che lo vede finire in ospedale. Cercando di coprire sé stesso ed Homer, Bart fa un reclamo per incontrare Gesù in Paradiso. Quando i produttori di Natale vogliono fargli un'offerta per un film, Bart inizia a sentirsi colpevole per aver ingannato.

Marge ed Homer diventano i concorrenti dello show americano The Amazing Place, il sogno di tutta la vita di Marge. Tuttavia Homer finisce per rovinare tutto, venendo così cacciato alla prima sfida e facendo arrabbiare Marge, specialmente dal momento in cui vengono a conoscenza del fatto che dovranno passare sei settimane nell'hotel dell'aeroporto. Quando gli viene offerta una seconda possibilità per sfidarsi tra di loro, Marge scambierà Homer con un altro partner, guastando l'intera competizione. Homer diventa tanto impassibile che per la prima volta, le persone provano dispiacere per lui e non per Marge.

Le storie questa volta sono quattro: -La zuppa verde di vongole

-L'invasione degli ultra-pod

-Multip-lisa-ta

-Geriatric Park

Homer viene licenziato dal signor Burns e deve trovarsi un altro lavoro. Comincia a lavorare in una start-up nel campo dell'alta tecnologia: la CarGo. Dopo averne visto i vantaggi, a questo lavoro si unisce anche Marge. Successivamente si uniscono anche gli impiegati della Centrale Nucleare del signor Burns. Quest'ultimo, insieme a Smithers, Homer e Marge (annoiati dalla manipolazione delle loro vite tramite le auto), manomettono e disattivano i sistemi di controllo della CarGo, nel frattempo andata in bancarotta. Così, alla fine, Homer chiede a Burns, invano, se ci fosse possibilità di trovare un impiego a lui e a Marge insieme.

On a mission to play hardcore pranks, Bart, Nelson and Milhouse get Moe a mail-order bride on the Dark Web.

Marge wants a job, and stumbles into becoming a plastic food storage container-selling drag queen. Meanwhile, Lisa tries to make the world better in the style of "Amelie"

Homer finds his calling as a TV recapper, but his harsh grading causes a brawl with Krusty. After almost killing Homer, Krusty hides out at a real circus, and finds happiness there.

Lisa and Homer's bond gets stronger when they start spending real quality time together, and Bart feels neglected. So Marge tries to help Homer balance his attention between the kids.

After a failed Black Friday shopping spree, Marge is determined to fix Christmas; Homer and the kids surprise Marge with a vacation to a Florida resort.

When Marge and Homer leave Grampa to baby-sit the kids, some little green army men trigger a PTSD episode, sending the family on a journey to Grampa's past and the time period when he was a post-war toy model.

When Lisa spots a new best friend from the window of the bus, she gets a taste of what life could be like with a different, more cultured family.

Homer angers Marge by binging their favorite show without her, and has to pick up a new skill in order to make amends. Meanwhile, Bart prepares to compete in "Krusty's Holiday Trample".

Krusty reveals the untold story of his past in his movie "The Sands of Space". While working as personal assistants on the movie, Bart and Lisa learn about the early years of their parents' relationship.

Comic Book Guy sues Homer for joyriding in his car. Meanwhile, Guillermo del Toro saves Mr. Burns from his troubles with the law.

When a romantic night ends in injury, Marge recovers by taking up kite boarding while Homer bonds with his hallucinated hernia; Lisa attempts to fix her parents' strained relationship by seeking advice from an unlikely source.

As Bart begins to excel in video game competitions, Homer discovers a passion for coaching him; Lisa attempts to bring Homer back to reality, but the plan causes chaos.

Krusty releases an all-female reboot of “Itchy and Scratchy,” so Bart and his crew of all-male friends decide to boycott the show. After Bart’s friends turn on him for laughing at the reboot, Bart joins a woke group of sixth-grade girls who commit crimes against patriarchy.

Homer works extra shifts at the plant so Lisa can play in the Capitol City Philharmonic.

Marge becomes director of Springfield's local theater, armed with Lisa's script resembling "Hamilton"; Homer joins a baby class with Maggie, and he takes a liking to supervisor Chloe.

Lisa is mistakenly given political asylum in Canada during a family trip to Niagara Falls; Homer goes to a “Daddy and Me” class with Maggie.

The documentary crime series “Dateline: Springfield” goes in-depth to solve the case of Lisa’s missing college fund.

Marge starts a business selling healing crystals to the naive mothers of Springfield when Homer’s work cuts children’s health-care benefits, leading Marge to use the crystals as a cheaper solution for Bart’s ADD.