Michiko Daimon is een freelance chirurg. Ze wordt aangenomen in het academisch ziekenhuis om verschillende artsen te vervangen die hun functie hebben verlaten. Daimon is niet een typische chirurg. Ze geeft niets om hiërarchie, doet alleen wat een medische graad vereist, en maakt geen overuren. Haar honoraria zijn buitensporig hoog voor het ziekenhuis, omdat ze nooit faalt in haar operaties.

Ze schudt een ziekenhuis wakker door machtsstrijd tussen artsen en beoefent geneeskunde op hoog niveau, altijd ten behoeve van haar patiënten.

Daimon Michiko is a 37-year-old freelance surgeon who is part of a questionable “doctor placement service” that has her wander from hospital to hospital. The harsh environment at the hospitals led many doctors to retire from their positions, forcing hospitals to make use of said program to fill the empty spots at least temporary. However, Michiko doesn’t look like a doctor at all with her flashy clothes and eccentric attitude. In the first episode she raises objections to a certain operation which is planned to be done by the head of a hospital who hasn’t performed an operation for a very long time. This causes Michiko to incur odium at the hospital, however, everyone becomes frozen when Michiko points out the outdated skills of the director. She also holds a scrupulous compliance when it comes to her working hours, never does any unnecessary chores that don’t require a medical license, and couldn’t care less about the power struggles within the hospitals. Nobody knows how she acquired such a top-level skill that allows her to claim exorbitant sums as reward, but her private life is an even greater mystery to everyone around her. Tanaka plays a rookie surgeon, Uchida an anesthetist, Kishibe the head of the placement service, and Ito the head of the surgical department of this institution.

Michiko Daimon est une chirurgienne freelance. Elle est embauchée à l'hôpital universitaire pour remplacer plusieurs médecins qui ont quitté leur poste. Daimon n'est pas une chirurgienne typique. Elle n'a cure de la hiérarchie, ne fait que ce qui nécessite un diplôme de médecine, ne fait pas d'heures supplémentaires. Ses honoraires sont exorbitants pour l’hôpital car elle n'échoue jamais dans ses opérations.

Bousculant un hôpital sclérosé par les luttes de pouvoir entre médecins, elle pratique une médecine de haut niveau toujours au bénéfice de ses patients.

「私、失敗しないので」

目の前の患者を救うというポリシーのもと、圧倒的な腕で数多くの命を救いながら、金と欲にまみれた医療界にも鋭いメスを入れてきたフリーランスの天才外科医・大門未知子。群れを嫌い、権威を嫌い、束縛を嫌い、専門医のライセンスと叩き上げのスキルだけが彼女の武器…成功率や生存率が低く、術式が確立されていない危険なオペにも、臆することなく挑戦する医師たち。彼らは敬意と皮肉を込めてこう呼ばれている ―― 命を天秤にかける悪魔の外科医。またの名を「ドクターＸ」。そんなドクターＸの一人・米倉演じる大門未知子が、病院組織を舞台に数々の騒動を巻き起こしながらも、外科医の本質である手術や治療に一切の妥協を許さず突き進んだ前作。今作も、専門医のライセンスと叩き上げのスキルだけを武器に戦う型破りなヒロインの活躍が、閉塞感に包まれた日常に風穴を開ける！

受医疗制度改革的影响，曾经显赫一时的大学医院——帝都医科大学第三医院因医疗状况恶化和工作压力过大导致卓越出众的医师纷纷离职，人才流失造成医院的发展岌岌可危。在此背景之下，不属于大学医院和医局体制的自由医生应运而生。美丽性感的外科医生大门未知子便是自由医生的一员，她被人称作“Doctor X”，讨厌拉帮结派和医疗腐败，有如一朵盛开在泥沼中的带刺野玫瑰。未知子的到来给了这间迂腐凝滞的一前所未有的冲击，而她过硬的外科技术和理论知识又令同侪钦佩与嫉妒。 战战兢兢的新人森本光负责带领这名曾涉足海外的传奇人物。未知子将迎战各种疑难杂症以及无形的阻碍。

劇情講述的是直言敢諫的派遣醫師大門未知子，討厭結群、討厭權力、討厭束縛，以其專業執照以及高超的技術作為武器，勇於挑戰白色巨塔封建體系的故事。

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Daimon Michiko, hastaneden hastaneye dolaşan şüpheli bir “doktor yerleştirme servisinin” parçası olan 37 yaşında serbest çalışan bir cerrahtır. Michiko gösterişli kıyafetleri ve eksantrik tavrıyla hiç de doktora benzemiyor. Ayrıca çalışma saatlerine de titizlikle uyuyor, tıp lisansı gerektirmeyen gereksiz işleri asla yapmıyor ve hastanelerdeki güç mücadelelerini hiç umursamıyordu. Ödül olarak fahiş meblağlar talep etmesine izin veren böylesine üst düzey bir beceriyi nasıl edindiğini kimse bilmiyor, ancak özel hayatı etrafındaki herkes için daha da büyük bir gizem.